dgn-np:NP11671.RAugRrQjvrqBzBfj8sSqMqC4IFEaWwtNfcZoQ6Hw3Zkvs130_provenance {
dgn-np:NP11671.RAugRrQjvrqBzBfj8sSqMqC4IFEaWwtNfcZoQ6Hw3Zkvs130_assertion dcterms:description "[Treatment with arsenic trioxide (ATO; 2-200 microM) inhibited NF-kappaB activity in normal marrow, primary MDS, and ML1 cells, even in the presence of exogenous TNF-alpha (20 ng/mL), and down-regulated NF-kappaB-dependent antiapoptotic proteins, B-cell leukemia XL (Bcl-XL), Bcl-2, X-linked inhibitor of apoptosis (XIAP), and Fas-associated death domain (FADD)-like interleukin-1beta-converting enzyme (FLICE) inhibitory protein (FLIP), leading to apoptosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en ;
wi:evidence dgn-void:source_evidence_curated ;
sio:SIO_000772 miriam-pubmed:16105982 ;
prov:wasDerivedFrom dgn-void:ctd_human-20130708 ;
prov:wasGeneratedBy eco:ECO_0000218 .
dgn-void:ctd_human-20130708 pav:importedOn "2013-07-24"^^
xsd:date .
dgn-void:source_evidence_curated a eco:ECO_0000205 ;
rdfs:comment "Gene-disease associations manually curated."@en ;
rdfs:label "DisGeNET evidence - CURATED"@en .
}