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[Previously, we found that the Acr-DNA binding pattern in the human p53 gene coincides with the p53 mutational pattern in CS-related lung cancer; hence, we proposed that Acr is a major lung cancer etiological agent [ Feng , Z. , Hu , W. , Hu , Y. , and Tang , M.-s. ( 2006 ) Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair .Proc.Natl.Acad.Sci.U.S.A. 103 , 15404 - 15409 ].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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