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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAvBEBCPcVYunPSHuSnCwnj5xtE1WOM7D0os4fTJVP0o0#_7 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAvBEBCPcVYunPSHuSnCwnj5xtE1WOM7D0os4fTJVP0o0#_6 http://www.w3.org/ns/prov#value The GnRHR is also expressed in non-pituitary cells and was found to be involved in the inhibition of cell proliferation in certain cells. Therefore, GnRHR represents a potential target for GnRH-analogs used for cancer treatment. Interestingly, the signaling mechanism of the GnRHR in other cell types significantly differs from that in pituitary cells. Studies conducted in GnRHR-expressing COS7 cells have shown that GnRHR transmits its signals mainly via Gi, EGF receptor, c-Src, and is not dependent on PKC. http://www.tkuhn.ch/bel2nanopub/RAvBEBCPcVYunPSHuSnCwnj5xtE1WOM7D0os4fTJVP0o0#_6 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/11750725 http://www.tkuhn.ch/bel2nanopub/RAvBEBCPcVYunPSHuSnCwnj5xtE1WOM7D0os4fTJVP0o0#_7 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAvBEBCPcVYunPSHuSnCwnj5xtE1WOM7D0os4fTJVP0o0#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/11750725 http://www.tkuhn.ch/bel2nanopub/RAvBEBCPcVYunPSHuSnCwnj5xtE1WOM7D0os4fTJVP0o0#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAvBEBCPcVYunPSHuSnCwnj5xtE1WOM7D0os4fTJVP0o0#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAvBEBCPcVYunPSHuSnCwnj5xtE1WOM7D0os4fTJVP0o0#_6 http://www.tkuhn.ch/bel2nanopub/RAvBEBCPcVYunPSHuSnCwnj5xtE1WOM7D0os4fTJVP0o0#pubinfo http://www.tkuhn.ch/bel2nanopub/RAvBEBCPcVYunPSHuSnCwnj5xtE1WOM7D0os4fTJVP0o0 http://purl.org/dc/terms/created 2014-07-03T14:29:59.790+02:00 http://www.tkuhn.ch/bel2nanopub/RAvBEBCPcVYunPSHuSnCwnj5xtE1WOM7D0os4fTJVP0o0 http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAvBEBCPcVYunPSHuSnCwnj5xtE1WOM7D0os4fTJVP0o0 http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234