@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAvN8bNR1eQONmMYNkzNhxEf7BnrxOaDXoa7XJntLtyw8> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAvN8bNR1eQONmMYNkzNhxEf7BnrxOaDXoa7XJntLtyw8#> .
@prefix beldoc: <http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix mesh: <http://purl.bioontology.org/ontology/MSH/> .
@prefix RNA: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_33697> .
@prefix rgd: <http://rgd.mcw.edu/rgdweb/report/gene/main.html?id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:_1 geneProductOf: rgd:620925;
    a RNA: .
  
  sub:_2 occursIn: mesh:D018482, species:10116;
    rdf:object sub:_1;
    rdf:predicate belv:increases;
    rdf:subject mesh:D015444;
    a rdf:Statement .
  
  sub:assertion rdfs:label "bp(MESHPP:Exercise) -> r(RGD:Ppargc1a)" .
}

sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements.";
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
    dce:title "BEL Framework Large Corpus Document";
    pav:authoredBy sub:_4;
    pav:version "1.4" .
  
  sub:_3 prov:value "ALA synthase and GLUT4 have short half-lives and increase rapidly in skeletal muscle in response to exercise (17, 36). The concentrations of ALA synthase and GLUT4 after 5 days of exercise probably represent their new steady-state concentration, as there was no significant difference between their concentrations after 3 days (data not shown) and after 5 days of exercise. Cytochrome c and citrate synthase appear to have half-lives in the range of 6-8 days, and they increase with a half-time of 7 days in response to a constant daily exercise stimulus (9). There is no previous information regarding the time course of the adaptive increase in muscle cytochrome oxidase subunit I to exercise; however, it appears from the present results to increase at least as rapidly as citrate synthase and cytochrome c. The magnitude of this adaptive response is similar to that induced by 6 days of a treadmill running program used in earlier studies (36). PGC-1 Gene transcription in skeletal muscle increases rapidly after a bout of exercise The level of PGC-1 mRNA was determined by Northern blot using a full-length PGC-1 probe. PGC-1 from triceps muscles of sedentary rats migrates as a single band on a 1% agarose gel (above the 28S rRNA band) (Fig. 2). There was a twofold increase in the fulllength PGC-1 mRNA evident in muscles taken 6 h after exercise (Fig. 2).";
    prov:wasQuotedFrom pubmed:12468452 .
  
  sub:_4 rdfs:label "Selventa" .
  
  sub:assertion prov:hadPrimarySource pubmed:12468452;
    prov:wasDerivedFrom beldoc:, sub:_3 .
}

sub:pubinfo {
  this: dct:created "2014-07-03T14:30:07.698+02:00"^^xsd:dateTime;
    pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}