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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAvbINdBmkkq58iFi6NDrDjnX6Tfz3lexVVcFe7Eyczfo#_5 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAvbINdBmkkq58iFi6NDrDjnX6Tfz3lexVVcFe7Eyczfo#_4 http://www.w3.org/ns/prov#value IGF-1 receptor signaling when blocked with anti IGF-1R alpha neutralizing antibody, and when, either the 2.6 kb or the 0.35 kb VPF/VEGF reporter construct was transfected into AsPC-1 cells. The reporter activity of the 2.6 kb VPF/VEGF promoter showed a 50% decrease, and the 0.35kb VPF/VEGF promoter (mainly Sp1 binding sites) showed a 40% decrease compared with that of the IgG control. 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