sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_8 ;
    pav:version "1.4" .
  sub:_7 prov:value "Carson et al. (1995) concluded that SRE1 is a hypertrophy regulatory element that activates specific contractile protein genes to produce more mRNA in response to overload conditions. Serum response factor (SRF) is a transcription factor that homodimerizes to SRE1 on the skeletal alpha-actin gene (Lee et al. 1992). Increases in the quantity (Carson et al. 1995), and potentially the post-translational status (Fluck et al. 1999), of SRF were noted in hypertrophying muscles. An increase in SRF transcriptional activity should enhance transcription of skeletal alpha-actin mRNA. Therefore, it is likely that during the late phases of a hypertrophic stimulus, transcription of the alpha-actin gene is an important contributor to muscle hypertrophy." ;
    prov:wasQuotedFrom pubmed:12205177 .
  sub:_8 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:12205177 ;
    prov:wasDerivedFrom beldoc: , sub:_7 .
}