@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAvr_quqQVw3JQy55kRbjv9JPpTeRCawO8N8O3TrhH3CI> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAvr_quqQVw3JQy55kRbjv9JPpTeRCawO8N8O3TrhH3CI#> .
@prefix beldoc: <http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix proteinModification: <http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00000> .
@prefix psimod: <http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix nch: <http://resource.belframework.org/belframework/1.0/namespace/selventa-named-human-complexes/> .
@prefix ProteinComplex: <http://amigo.geneontology.org/amigo/term/GO:0043234> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix mesh: <http://purl.bioontology.org/ontology/MSH/> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .
sub:Head {
   this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
   nch:AP-1%20Complex a ProteinComplex: .
  sub:_1 belv:variantOf hgnc:6204 ;
    a proteinModification: , psimod:00696 .
  sub:_2 hasAgent: nch:AP-1%20Complex ;
    a go:0042789 .
  sub:_3 occursIn: mesh:D001940 , mesh:D003106 , species:9606 ;
    rdf:object sub:_2 ;
    rdf:predicate belv:directlyIncreases ;
    rdf:subject sub:_1 ;
    a rdf:Statement .
  sub:assertion rdfs:label "p(HGNC:JUN,pmod(P,S)) => tscript(complex(NCH:\"AP-1 Complex\"))" .
}
sub:provenance {
   beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_5 ;
    pav:version "1.4" .
  sub:_4 prov:value "Multiple extracellular stimuli like peptide growth factors, steroid hormones, and environmental stresses activate AP-1 through JNK. c-Jun is a specific substrate and functional endpoint for JNK. Hence, by activating c-Jun, JNK actually controls various AP-1-related cellular processes such as proliferation, differentiation, transformation, apoptosis, and development. Proliferation of prostate cancer cell lines is highly correlated with serum-supported JNK activity, and growth of prostate carcinoma cells in vitro and in vivo requires JNK" ;
    prov:wasQuotedFrom pubmed:14587863 .
  sub:_5 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:14587863 ;
    prov:wasDerivedFrom beldoc: , sub:_4 .
}
sub:pubinfo {
   this: dct:created "2014-07-03T14:30:17.909+02:00"^^xsd:dateTime ;
    pav:createdBy orcid:0000-0001-6818-334X , orcid:0000-0002-1267-0234 .
}