@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix this: <http://purl.org/np/RAytl9AFqJs8aXvS34NgLmtChr5_wZX4Cg1uGI9ntzZ7M> .
@prefix sub: <http://purl.org/np/RAytl9AFqJs8aXvS34NgLmtChr5_wZX4Cg1uGI9ntzZ7M#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix nkg: <https://w3id.org/um/neurodkg/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .
sub:Head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
  <http://purl.obolibrary.org/obo/MONDO_0005052> biolink:category biolink:Disease .
  sub:association rdf:object <http://purl.obolibrary.org/obo/MONDO_0005052> ;
    rdf:predicate biolink:treats ;
    rdf:subject <https://go.drugbank.com/drugs/DB00904> ;
    a rdf:Statement ;
    rdfs:label "Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder which represents a major cost to healthcare services. IBS-D patients represent about one-third of the IBS population and are currently treated with antispasmodics, loperamide, bile acid sequestrants and antidepressants. Alosetron and rifaximin are also available in USA, ramosetron in Japan, Korea and Thailand and ondansetron as an off-label treatment." ;
    biolink:association_type biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation ;
    biolink:has_population_context sub:cohort ;
    biolink:provided_by <https://w3id.org/um/NeuroDKG> ;
    biolink:publications <https://pubmed.ncbi.nlm.nih.gov/28276811/> ;
    biolink:relation nkg:OffLabelIndication .
  sub:cohort rdfs:label "Adults" ;
    biolink:category biolink:Cohort .
  <https://go.drugbank.com/drugs/DB00904> biolink:category biolink:Drug .
}
sub:provenance {
  sub:assertion prov:wasAttributedTo orcid:0000-0002-7641-6446 .
}
sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA" ;
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCamPJb4SzqpLXn//XJ5dlVfzz6QI+RPmiJTLXF/by2JR7sHMKRsCQDFsYMlq8zGHghOIkjRP9dpLZUtZzUcHt3MXiFKEPo8eGzUe9p+JXKFC8xxkJr94z2vq6IdMf71Iu1GH8SeDAKt/DgYO4zNaw8VuXvxnZRewKZSA+u8zWPVwIDAQAB" ;
    npx:hasSignature "L7B3xksOrZtTwhr+neU351oQTkKxdQ8d6a7uB9vlY5FxCWACAqmvtx4gDCK8OTP1qgKrtMHNis/p13yNWgfZjSb2q7c9F/CjxDznQctKGkNa3ny8089AEfMTBl7XUhx/OwnzPrsPBm9ZVzyQZDuz8mJZ+eLSRgXl8+tIIr2JWRc=" ;
    npx:hasSignatureTarget this: .
  this: dcterms:created "2021-05-28T17:40:31.342+02:00"^^xsd:dateTime ;
    dcterms:creator orcid:0000-0002-7641-6446 ;
    nt:wasCreatedFromProvenanceTemplate <http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM> ;
    nt:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM> ;
    nt:wasCreatedFromTemplate <http://purl.org/np/RAManV5GZI01JKzW_IPcfOXoiFTcZMmsV7qTCLkdzr4Gs> .
}