@prefix biolink: <
https://w3id.org/biolink/vocab/
> .
@prefix dcterms: <
http://purl.org/dc/terms/
> .
@prefix this: <
http://purl.org/np/RAytl9AFqJs8aXvS34NgLmtChr5_wZX4Cg1uGI9ntzZ7M
> .
@prefix sub: <
http://purl.org/np/RAytl9AFqJs8aXvS34NgLmtChr5_wZX4Cg1uGI9ntzZ7M#
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix nt: <
https://w3id.org/np/o/ntemplate/
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix orcid: <
https://orcid.org/
> .
@prefix nkg: <
https://w3id.org/um/neurodkg/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix npx: <
http://purl.org/nanopub/x/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
<
http://purl.obolibrary.org/obo/MONDO_0005052
>
biolink:category
biolink:Disease
.
sub:association
rdf:object
<
http://purl.obolibrary.org/obo/MONDO_0005052
> ;
rdf:predicate
biolink:treats
;
rdf:subject
<
https://go.drugbank.com/drugs/DB00904
> ;
a
rdf:Statement
;
rdfs:label
"Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder which represents a major cost to healthcare services. IBS-D patients represent about one-third of the IBS population and are currently treated with antispasmodics, loperamide, bile acid sequestrants and antidepressants. Alosetron and rifaximin are also available in USA, ramosetron in Japan, Korea and Thailand and ondansetron as an off-label treatment." ;
biolink:association_type
biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation
;
biolink:has_population_context
sub:cohort
;
biolink:provided_by
<
https://w3id.org/um/NeuroDKG
> ;
biolink:publications
<
https://pubmed.ncbi.nlm.nih.gov/28276811/
> ;
biolink:relation
nkg:OffLabelIndication
.
sub:cohort
rdfs:label
"Adults" ;
biolink:category
biolink:Cohort
.
<
https://go.drugbank.com/drugs/DB00904
>
biolink:category
biolink:Drug
.
}
sub:provenance
{
sub:assertion
prov:wasAttributedTo
orcid:0000-0002-7641-6446
.
}
sub:pubinfo
{
sub:sig
npx:hasAlgorithm
"RSA" ;
npx:hasPublicKey
"MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCamPJb4SzqpLXn//XJ5dlVfzz6QI+RPmiJTLXF/by2JR7sHMKRsCQDFsYMlq8zGHghOIkjRP9dpLZUtZzUcHt3MXiFKEPo8eGzUe9p+JXKFC8xxkJr94z2vq6IdMf71Iu1GH8SeDAKt/DgYO4zNaw8VuXvxnZRewKZSA+u8zWPVwIDAQAB" ;
npx:hasSignature
"L7B3xksOrZtTwhr+neU351oQTkKxdQ8d6a7uB9vlY5FxCWACAqmvtx4gDCK8OTP1qgKrtMHNis/p13yNWgfZjSb2q7c9F/CjxDznQctKGkNa3ny8089AEfMTBl7XUhx/OwnzPrsPBm9ZVzyQZDuz8mJZ+eLSRgXl8+tIIr2JWRc=" ;
npx:hasSignatureTarget
this:
.
this:
dcterms:created
"2021-05-28T17:40:31.342+02:00"^^
xsd:dateTime
;
dcterms:creator
orcid:0000-0002-7641-6446
;
nt:wasCreatedFromProvenanceTemplate
<
http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM
> ;
nt:wasCreatedFromPubinfoTemplate
<
http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM
> ;
nt:wasCreatedFromTemplate
<
http://purl.org/np/RAManV5GZI01JKzW_IPcfOXoiFTcZMmsV7qTCLkdzr4Gs
> .
}