@prefix this: . @prefix sub: . @prefix beldoc: . @prefix rdfs: . @prefix rdf: . @prefix xsd: . @prefix dct: . @prefix dce: . @prefix pav: . @prefix np: . @prefix belv: . @prefix prov: . @prefix Protein: . @prefix hgnc: . @prefix geneProductOf: . @prefix mesh: . @prefix species: . @prefix occursIn: . @prefix pubmed: . @prefix orcid: . sub:Head { this: np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:pubinfo; a np:Nanopublication . } sub:assertion { sub:_1 geneProductOf: hgnc:936; a Protein: . sub:_2 occursIn: species:9606; rdf:object mesh:D017209; rdf:predicate belv:increases; rdf:subject sub:_1; a rdf:Statement . sub:assertion rdfs:label "p(HGNC:BAD) -> bp(MESHPP:Apoptosis)" . } sub:provenance { beldoc: dce:description "Approximately 61,000 statements."; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved."; dce:title "BEL Framework Large Corpus Document"; pav:authoredBy sub:_4; pav:version "1.4" . sub:_3 prov:value "This modification is necessary for the association of BAD with the 14-3-3 proteins, which prevents BAD translocation to the mitochondria and its interaction with Bcl-XL or Bcl-2 (52, 19), thus allowing the latter proteins to promote cell survival. least as effectively as the wild-type protein, and is more potent than wild-type BAD in inducing cytochrome c release. Phosphorylation of BAD correlates with its ability to interact with 14-3-3 beta, an association necessary for sequestration of BAD in the cytoplasm WT, mutated, and truncated forms of BAD all induced the release of cytochrome c from isolated mitochondria"; prov:wasQuotedFrom pubmed:11287608 . sub:_4 rdfs:label "Selventa" . sub:assertion prov:hadPrimarySource pubmed:11287608; prov:wasDerivedFrom beldoc:, sub:_3 . } sub:pubinfo { this: dct:created "2014-07-03T14:29:55.342+02:00"^^xsd:dateTime; pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 . }