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[Instead, SIM+MET treatment led to Ripk1- and Ripk3-dependent necrosis by 48-96?h, determined by propidium iodide-Annexin V flow cytometry, increase in Ripk1 and Ripk3 protein expression, necrosome formation, HMGB-1 extracellular release, and necrotic induction and viability rescue with necrostatin-1 and Ripk3-targeting siRNA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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