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http://www.w3.org/1999/02/22-rdf-syntax-ns#value Abstract http://www.tkuhn.ch/bel2nanopub/RAzoa-cMMh2EDG2stv9Vs8TM-rl2BAU9HwfRR9D7nf55E#assertion http://www.w3.org/2000/01/rdf-schema#label complex(p(HGNC:VTN),p(HGNC:ITGAV),p(HGNC:ITGB3)) -> (kin(p(HGNC:KDR)) -> bp(GO:"cell migration")) http://www.tkuhn.ch/bel2nanopub/RAzoa-cMMh2EDG2stv9Vs8TM-rl2BAU9HwfRR9D7nf55E#assertion http://www.w3.org/2000/01/rdf-schema#label kin(p(HGNC:KDR)) -> bp(GO:"cell migration") http://www.tkuhn.ch/bel2nanopub/RAzoa-cMMh2EDG2stv9Vs8TM-rl2BAU9HwfRR9D7nf55E#provenance http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 2000 hand curated statements drawn from 57 PubMeds. http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All Rights Reserved. http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Small Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/terms/license Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAzoa-cMMh2EDG2stv9Vs8TM-rl2BAU9HwfRR9D7nf55E#_11 http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/pav/version 1.6 http://www.tkuhn.ch/bel2nanopub/RAzoa-cMMh2EDG2stv9Vs8TM-rl2BAU9HwfRR9D7nf55E#_10 http://www.w3.org/ns/prov#value Here we examine the nature of the physical interaction between the αvβ3 integrin and two receptor tyrosine kinases (RTKs), the platelet-derived growth factor receptor β (PDGF-Rβ) and the vascular endothelial growth factor receptor 2 (VEGF-R2, also known as KDR and flk-1). Both of these RTKs associate with the αvβ3 integrin but do not associate with β1 integrins. Furthermore, growth factor stimulation of these RTKs promotes increased cell proliferation and migration when cells are attached to the αvβ3 ligand, vitronectin. http://www.tkuhn.ch/bel2nanopub/RAzoa-cMMh2EDG2stv9Vs8TM-rl2BAU9HwfRR9D7nf55E#_10 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/10964931 http://www.tkuhn.ch/bel2nanopub/RAzoa-cMMh2EDG2stv9Vs8TM-rl2BAU9HwfRR9D7nf55E#_11 http://www.w3.org/2000/01/rdf-schema#comment support@belframework.org http://www.tkuhn.ch/bel2nanopub/RAzoa-cMMh2EDG2stv9Vs8TM-rl2BAU9HwfRR9D7nf55E#_11 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAzoa-cMMh2EDG2stv9Vs8TM-rl2BAU9HwfRR9D7nf55E#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/10964931 http://www.tkuhn.ch/bel2nanopub/RAzoa-cMMh2EDG2stv9Vs8TM-rl2BAU9HwfRR9D7nf55E#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAzoa-cMMh2EDG2stv9Vs8TM-rl2BAU9HwfRR9D7nf55E#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAzoa-cMMh2EDG2stv9Vs8TM-rl2BAU9HwfRR9D7nf55E#_10 http://www.tkuhn.ch/bel2nanopub/RAzoa-cMMh2EDG2stv9Vs8TM-rl2BAU9HwfRR9D7nf55E#pubinfo http://www.tkuhn.ch/bel2nanopub/RAzoa-cMMh2EDG2stv9Vs8TM-rl2BAU9HwfRR9D7nf55E http://purl.org/dc/terms/created 2014-07-03T14:29:31.717+02:00 http://www.tkuhn.ch/bel2nanopub/RAzoa-cMMh2EDG2stv9Vs8TM-rl2BAU9HwfRR9D7nf55E http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAzoa-cMMh2EDG2stv9Vs8TM-rl2BAU9HwfRR9D7nf55E http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234