Signaling by BMP

Transcriptional regulation of white adipocyte differentiation

Inositol phosphate metabolism

WNT ligand biogenesis and trafficking

Prolactin receptor signaling

Regulation of mRNA stability by proteins that bind AU-rich elements

Signaling by ERBB2

Influenza Life Cycle

Detoxification of Reactive Oxygen Species

Interleukin-2 family signaling

Sphingolipid metabolism

Activation of Matrix Metalloproteinases

Glycerophospholipid biosynthesis

Collagen biosynthesis and modifying enzymes

Visual phototransduction

MyD88:MAL(TIRAP) cascade initiated on plasma membrane

PIP3 activates AKT signaling

Binding and Uptake of Ligands by Scavenger Receptors

Pre-NOTCH Expression and Processing

Neurotoxicity of clostridium toxins

MyD88-independent TLR4 cascade

Host Interactions of HIV factors

alpha-linolenic (omega3) and linoleic (omega6) acid metabolism

Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways

Extracellular matrix organization

Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)

Growth hormone receptor signaling

Regulation of Hypoxia-inducible Factor (HIF) by oxygen

RAF/MAP kinase cascade

Degradation of the extracellular matrix

Cytosolic sensors of pathogen-associated DNA

Latent infection of Homo sapiens with Mycobacterium tuberculosis

HIV Life Cycle

Signaling by TGF-beta Receptor Complex

S Phase

Gamma carboxylation, hypusine formation and arylsulfatase activation

Vasopressin regulates renal water homeostasis via Aquaporins

Metabolism of non-coding RNA

Signaling by the B Cell Receptor (BCR)

Elastic fibre formation

The citric acid (TCA) cycle and respiratory electron transport

Arachidonic acid metabolism

Signaling by ERBB4

Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)

Insulin processing

Signaling by NOTCH1

Signaling by Hippo

Signaling by SCF-KIT

PI Metabolism

Fcgamma receptor (FCGR) dependent phagocytosis

Glycosaminoglycan metabolism

Fertilization

MyD88 dependent cascade initiated on endosome

SRP-dependent cotranslational protein targeting to membrane

Degradation of beta-catenin by the destruction complex

RNA polymerase II transcribes snRNA genes

Metabolism of polyamines

TNFR2 non-canonical NF-kB pathway

Signaling by FGFR4

Mitochondrial biogenesis

Uptake and function of anthrax toxins

Intra-Golgi and retrograde Golgi-to-ER traffic

Beta-catenin independent WNT signaling

Wax biosynthesis

Signaling by Leptin

Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism

tRNA modification in the mitochondrion

TCF dependent signaling in response to WNT

Signaling by FGFR2

EPH-Ephrin signaling

Sulfur amino acid metabolism

Oxidative Stress Induced Senescence

Metabolism of folate and pterines

Interleukin-20 family signaling

VEGFA-VEGFR2 Signaling Pathway

NIK-->noncanonical NF-kB signaling

Aflatoxin activation and detoxification

TNF signaling

MAPK6/MAPK4 signaling

Activation of anterior HOX genes in hindbrain development during early embryogenesis

Cardiac conduction

RHO GTPases Activate Formins

Serotonin Receptor 2 and ELK-SRF/GATA4 signaling

Resolution of Abasic Sites (AP sites)

Amyloid fiber formation

O-linked glycosylation

SUMOylation of DNA damage response and repair proteins

Cellular response to heat stress

Base-Excision Repair, AP Site Formation

C-type lectin receptors (CLRs)

Signaling by FGFR3

BMAL1:CLOCK,NPAS2 activates circadian gene expression

DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM

Retinoid metabolism and transport

Glyoxylate metabolism and glycine degradation

DNA Double Strand Break Response

Amine-derived hormones

TP53 Regulates Transcription of Cell Death Genes

Hedgehog 'off' state

HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)

POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation

RAF-independent MAPK1/3 activation

Hedgehog ligand biogenesis

Regulation of TP53 Activity through Methylation

Signaling by FGFR1

Macroautophagy

Vitamin D (calciferol) metabolism

RHO GTPases activate PKNs

Selenoamino acid metabolism

Amino acid synthesis and interconversion (transamination)

Cargo concentration in the ER

RHO GTPases regulate CFTR trafficking

RHO GTPases Activate NADPH Oxidases

Hedgehog 'on' state

Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3

SIDS Susceptibility Pathways

Regulation of TP53 Activity through Acetylation

Melanin biosynthesis

RHO GTPases Activate Rhotekin and Rhophilins

Synthesis of wybutosine at G37 of tRNA(Phe)

Mitophagy

XBP1(S) activates chaperone genes

ROS, RNS production in phagocytes

POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation

Oncogene Induced Senescence

Serotonin and anxiety-related events

SUMOylation of chromatin organization proteins

Threonine catabolism

tRNA modification in the nucleus and cytosol

Mismatch Repair

rRNA modification in the nucleus and cytosol

FasL/ CD95L signaling

Gene Silencing by RNA

Regulation of beta-cell development

Regulation of TP53 Expression and Degradation

Caspase activation via Dependence Receptors in the absence of ligand

Striated Muscle Contraction

TP53 Regulates Metabolic Genes

Senescence-Associated Secretory Phenotype (SASP)

TNFs bind their physiological receptors

Surfactant metabolism

TP53 Regulates Transcription of DNA Repair Genes

mTOR signalling

TET1,2,3 and TDG demethylate DNA

Caspase activation via Death Receptors in the presence of ligand

Regulation of TP53 Activity through Phosphorylation

Branched-chain amino acid catabolism

Fanconi Anemia Pathway

trans-Golgi Network Vesicle Budding

TP53 Regulates Transcription of Cell Cycle Genes

NoRC negatively regulates rRNA expression

Regulation of TP53 Activity through Association with Co-factors

Toll Like Receptor 3 (TLR3) Cascade

TRAIL signaling

Serotonin Receptor 2 and STAT3 Signaling

Lysosomal oligosaccharide catabolism

HDR through MMEJ (alt-NHEJ)

RHO GTPases Activate WASPs and WAVEs

Nonhomologous End-Joining (NHEJ)

Class I MHC mediated antigen processing & presentation

Sialic acid metabolism

tRNA processing in the nucleus

RHO GTPases activate PAKs

Miscellaneous transport and binding events

Mitochondrial translation

RORA activates gene expression

PRC2 methylates histones and DNA

SUMOylation of DNA replication proteins

Metallothioneins bind metals

RHO GTPases Activate ROCKs

RHO GTPases activate CIT

Serotonin Receptor 4/6/7 and NR3C Signaling

ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression

Synthesis, secretion, and deacylation of Ghrelin

RHO GTPases activate IQGAPs

Major pathway of rRNA processing in the nucleolus and cytosol

Regulated Necrosis

SUMOylation of RNA binding proteins

Interleukin-17 signaling

DNA Damage/Telomere Stress Induced Senescence

Smooth Muscle Contraction

DNA methylation

Protein repair
SUMOylation of transcription factors
SIRT1 negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression