[Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

Gene-disease associations manually curated.
DisGeNET evidence - CURATED

[High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Triggering CD40 on endothelial cells contributes to tumor growth.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[(1) Patients with primary (n=13) and secondary (n=11) PAH but not those with chronic thromboembolic pulmonary hypertension (n=8) had increased plasma levels of soluble (s) CD40L compared with control subjects (n=8).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Activation of CD40 with platelet derived CD154 promotes reactive oxygen species dependent death of human hepatocytes during hypoxia and reoxygenation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Finally, A3D8 induces apoptosis in all-trans-retinoic acid-resistant NB4-derived cells and in APL primary blasts, characterizing the A3D8 anti-CD44 mAb as a novel class of apoptosis-inducing agent in APL.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Down-regulation of CD44 contributes to the differentiation of HL-60 cells induced by ATRA or HMBA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Reciprocal changes of CD44 and GAP-43 expression in the dentate gyrus inner molecular layer after status epilepticus in mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Familial haemolytic uraemic syndrome and an MCP mutation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Inflammation and apoptosis in aortic tissues of aged type II diabetes: amelioration with alpha-lipoic acid through phosphatidylinositol 3-kinase/Akt- dependent mechanism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[These results indicate a critical role for CD69 in neutrophil function in arthritis induction during the effector phase.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Dual role of macrophage migration inhibitory factor (MIF) in human breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Blood gene expression markers to detect and distinguish target organ toxicity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Critical role of PI3K signaling for NF-kappaB-dependent survival in a subset of activated B-cell-like diffuse large B-cell lymphoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Lipoprotein lipase mediates hepatitis C virus (HCV) cell entry and inhibits HCV infection.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Furthermore, we have found that the mRNA and protein level of CD82 in decidua of the miscarriage is significantly higher than that of the normal early pregnancy, which implies that the abnormal higher CD82 expression in decidua restricts appropriate invasion of trophoblasts that leads to early pregnancy wastage.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Gene expression in cultured endometrium from women with different outcomes following IVF.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Pharmacologic inhibition of epigenetic modifications, coupled with gene expression profiling, reveals novel targets of aberrant DNA methylation and histone deacetylation in lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Retinoic acid represses a cassette of candidate pluripotency chromosome 12p genes during induced loss of human embryonal carcinoma tumorigenicity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mutations in the pre-replication complex cause Meier-Gorlin syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mechanisms of peripheral neuropathy associated with bortezomib and vincristine in patients with newly diagnosed multiple myeloma: a prospective analysis of data from the HOVON-65/GMMG-HD4 trial.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Progesterone resistance in PCOS endometrium: a microarray analysis in clomiphene citrate-treated and artificial menstrual cycles.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[E-cadherin transcriptional down-regulation by epigenetic and microRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Promoter methylation as a common mechanism for inactivating E-cadherin in human salivary gland adenoid cystic carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mutations of the E-cadherin gene in human gynecologic cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[E-cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Nitric oxide causes anoikis through attenuation of E-cadherin and activation of caspase-3 in human gastric carcinoma AZ-521 cells infected with Mycoplasma hyorhinis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Manganese superoxide dismutase induces migration and invasion of tongue squamous cell carcinoma via H2O2-dependent Snail signaling.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Absence of E-cadherin expression distinguishes noncohesive from cohesive pancreatic cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced prostate carcinogenesis in CYP1A-humanized mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The E-cadherin -160 C/A polymorphism and prostate cancer risk in white and black American men.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Reduced T-cadherin expression and promoter methylation are associated with the development and progression of hepatocellular carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Interestingly, mean CDH13 NMV was significantly lower in short-segment than in long-segment BE, a known clinical risk factor for neoplastic progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Molecular analysis of xenograft models of human cancer cachexia--possibilities for therapeutic intervention.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Substance dependence low-density whole genome association study in two distinct American populations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[cDNA microarray profiling of rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 7,12-dimethylbenz[a]anthracene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[We screened a population of 92 patients with classic/atypical Rett syndrome, 17 Angelman/Angelman-like patients and six idiopathic autistic patients for CDKL5 mutations and exon deletions and identified seven novel mutations: six in the Rett subset and one in an Angelman patient.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Carcinogenicity of dimethylarsinic acid in male F344 rats and genetic alterations in induced urinary bladder tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Experimental gene therapy using p21Waf1 gene for esophageal squamous cell carcinoma by gene gun technology.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Moreover, we used a combination of gene expression profiling of the response of cells in culture to sulindac and the response of the human mucosa in subjects treated with sulindac for 1 month, coupled with a mouse genetic model approach, to identify the cyclin dependent kinase inhibitor p21(WAF1/Cip1) as an important suppressor of Apc-initiated intestinal tumor formation and a necessary component for tumor inhibition by sulindac.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[p21 and mTERT are novel markers for determining different ischemic time periods in renal ischemia-reperfusion injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Microarray analysis of gene expression in peripheral blood mononuclear cells from dioxin-exposed human subjects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A pathway in quiescent cells that controls p27Kip1 stability, subcellular localization, and tumor suppression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[CDKN1A and CDKN1B polymorphisms and risk of advanced prostate carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Evaluation of genetic alterations in cancer-related genes in lung and brain tumors from B6C3F1 mice exposed to 1,3-butadiene or chloroprene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Progressive silencing of p14ARF in oesophageal adenocarcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[We also show that CDKN2A and CDKN2B are upregulated in the retina of a rat model of glaucoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genome-wide association study identifies five susceptibility loci for glioma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[In a multivariate model, promoter methylation of the cyclin-dependent kinase inhibitor 2A gene p16, the H-cadherin gene CDH13, the Ras association domain family 1 gene RASSF1A, and the adenomatous polyposis coli gene APC in tumors and in histologically tumor-negative lymph nodes was associated with tumor recurrence, independently of NSCLC stage, age, sex, race, smoking history, and histologic characteristics of the tumor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The molecular mechanisms of oncogenesis in mesothelioma involve the loss of negative regulators of cell growth including p16INK4a.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[These results indicate that methylation of p16 gene is essential important in the pathogenesis of MM and may provide a new diagnostic technique and drug target for the treatment of MM.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Inactivation of the CDKN2A and the p53 tumour suppressor genes in external genital carcinomas and their precursors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Global gene expression profiling of chemically induced rat mammary gland carcinomas and adenomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Varied pathways of stage IA lung adenocarcinomas discovered by integrated gene expression analysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genomic profile of Toll-like receptor pathways in traumatically brain-injured mice: effect of exogenous progesterone.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Phenotypic variability of the cat eye syndrome. Case report and review of the literature.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[CECR2, a protein involved in neurulation, forms a novel chromatin remodeling complex with SNF2L.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Prediction of metastatic relapse in node-positive breast cancer: establishment of a clinicogenomic model after FEC100 adjuvant regimen.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mutations in CEP57 cause mosaic variegated aneuploidy syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genome wide association for addiction: replicated results and comparisons of two analytic approaches.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Human carboxylesterase 1: from drug metabolism to drug discovery.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Two CES1 gene mutations lead to dysfunctional carboxylesterase 1 activity in man: clinical significance and molecular basis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Moreover, the dysregulation of genes such as CES1 and APOE seems to be associated with some physiopathological markers of insulin resistance and cardiovascular risk factors in obesity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Cardioplegia prevents ischemia-induced transcriptional alterations of cytoprotective genes in rat hearts: a DNA microarray study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[CFC1 mutations in patients with transposition of the great arteries and double-outlet right ventricle.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Deficient alternative complement pathway activation due to factor D deficiency by 2 novel mutations in the complement factor D gene in a family with meningococcal infections.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A family with complement factor D deficiency.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Heterozygous and homozygous factor h deficiencies associated with hemolytic uremic syndrome or membranoproliferative glomerulonephritis: report and genetic analysis of 16 cases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Variants in the factor H gene (CFH, also known as HF1), which encodes a major inhibitor of the alternative complement pathway, are associated with the risk for developing AMD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Expression, purification, cocrystallization and preliminary crystallographic analysis of sucrose octasulfate/human complement regulator factor H SCRs 6-8.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A rare penetrant mutation in CFH confers high risk of age-related macular degeneration.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genome-wide association study identifies susceptibility loci for IgA nephropathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A functional variant in the CFI gene confers a high risk of age-related macular degeneration.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Glycolytic cancer associated fibroblasts promote breast cancer tumor growth, without a measurable increase in angiogenesis: evidence for stromal-epithelial metabolic coupling.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Proteome analysis of hepatocellular carcinoma cell strains, MHCC97-H and MHCC97-L, with different metastasis potentials.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Treatment with arsenic trioxide (ATO; 2-200 microM) inhibited NF-kappaB activity in normal marrow, primary MDS, and ML1 cells, even in the presence of exogenous TNF-alpha (20 ng/mL), and down-regulated NF-kappaB-dependent antiapoptotic proteins, B-cell leukemia XL (Bcl-XL), Bcl-2, X-linked inhibitor of apoptosis (XIAP), and Fas-associated death domain (FADD)-like interleukin-1beta-converting enzyme (FLICE) inhibitory protein (FLIP), leading to apoptosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Molecular characterisation of 10 Dutch properdin type I deficient families: mutation analysis and X-inactivation studies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Sequence-based analysis of properdin deficiency: identification of point mutations in two phenotypic forms of an X-linked immunodeficiency.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[No detectable improvements in cystic fibrosis transmembrane conductance regulator by nasal aminoglycosides in patients with cystic fibrosis with stop mutations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Probing conformational rescue induced by a chemical corrector of F508del-cystic fibrosis transmembrane conductance regulator (CFTR) mutant.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Novel CFTR missense mutations in Brazilian patients with congenital absence of vas deferens: counseling issues.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Patients presenting with recurrent, `idiopathic` pancreatitis require CFTR function testing.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Hemiplegia after thyrotropin alfa in a hypothyroid patient with thyroid carcinoma metastatic to the brain.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Flowers of Hibiscus rosa-sinensis, a potential source of contragestative agent. III: Interceptive effect of benzene extract in mouse.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Characterization of arecoline-induced effects on cytotoxicity in normal human gingival fibroblasts by global gene expression profiling.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[CHD5 is the strongest candidate tumor suppressor gene that is deleted from 1p36.31 in neuroblastomas, and inactivation of the second allele may occur by an epigenetic mechanism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Phenotypic spectrum of CHARGE syndrome with CHD7 mutations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The CHEK2 1100delC mutation identifies families with a hereditary breast and colorectal cancer phenotype.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Previous studies of families with multiple cases of breast cancer have indicated that a frameshift alteration in the CHEK2 gene, 1100delC, is associated with an elevated frequency of breast cancer in such families, but the risk associated with the variant in other situations is uncertain.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A gene expression signature of acquired chemoresistance to cisplatin and fluorouracil combination chemotherapy in gastric cancer patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Exploiting the genomic sequence of chromosome 22, we looked for mutations in the exons and intron junctions of the CHK2 gene in DNA samples from 170 patients (57 osteosarcomas, 25 other sarcomas, 35 nonsmall-cell lung, 20 ovarian, and 33 breast cancers).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Additional screening for CHEK2 mutations in 149 families with familial prostate cancer revealed 11 mutations (5 unique) in nine families.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Relationship of aberrant DNA hypermethylation of CHFR with sensitivity to taxanes in endometrial cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Using immuno-histochemical staining for neuron-specific enolase (NSE), chromogranin A (ChrA), and synaptophysin (Syn), 29 (25%) NSCLC-ND were identified.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Type 1 Gaucher disease: null and hypomorphic novel chitotriosidase mutations-implications for diagnosis and therapeutic monitoring.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Variant between CPT1B and CHKB associated with susceptibility to narcolepsy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Correlation between expression of apoptosis-related gene pnas-2 and leukemia].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Inhibition of cholinephosphotransferase activity in lung injury induced by 2-chloroethyl ethyl sulfide, a mustard analog.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Benzamide protects delayed neuronal death and behavioural impairment in a mouse model of global cerebral ischemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Acetylcholine-induced seizure-like activity and modified cholinergic gene expression in chronically epileptic rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Scopolamine treatment and muscarinic receptor subtype-3 gene ablation augment azoxymethane-induced murine liver injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effect of M4-cholinoceptor blockade on haloperidol-produced catatonic syndrome in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Deletion of the M5 muscarinic acetylcholine receptor attenuates morphine reinforcement and withdrawal but not morphine analgesia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A novel signaling pathway: fibroblast nicotinic receptor alpha1 binds urokinase and promotes renal fibrosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[In this study we performed a comprehensive association analysis of the CHRNA5-CHRNA3-CHRNB4 gene cluster in the Collaborative Study on the Genetics of Alcoholism (COGA) families to investigate the role of genetic variants in risk for alcohol dependence.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Altered fast- and slow-twitch muscle fibre characteristics in female mice with a (S248F) knock-in mutation of the brain neuronal nicotinic acetylcholine receptor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A genotype-first approach for the molecular and clinical characterization of uncommon de novo microdeletion of 20q13.33.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genetic and pharmacological strategies identify a behavioral function of neuronal nicotinic receptors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Progesterone modulation of alpha5 nAChR subunits influences anxiety-related behavior during estrus cycle.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Alpha7 nicotinic receptor up-regulation in cholinergic basal forebrain neurons in Alzheimer disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Molecular analysis of nicotinic receptor expression in autism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[We identified 15q13.3 microdeletions encompassing the CHRNA7 gene in 12 of 1,223 individuals with idiopathic generalized epilepsy (IGE), which were not detected in 3,699 controls (joint P = 5.32 x 10(-8)).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Neurotoxicity induced by okadaic acid in the human neuroblastoma SH-SY5Y line can be differentially prevented by 7 and 2* nicotinic stimulation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[beta 2 nicotinic acetylcholine receptor subunit modulates protective responses to stress: A receptor basis for sleep-disordered breathing after nicotine exposure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effects of cigarette smoke exposure on nicotinic acetylcholine receptor subunits 7 and 2 in the sudden infant death syndrome (SIDS) brainstem.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The alpha3 and beta4 nicotinic acetylcholine receptor subunits are necessary for nicotine-induced seizures and hypolocomotion in mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mutations in the embryonal subunit of the acetylcholine receptor (CHRNG) cause lethal and Escobar variants of multiple pterygium syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Musculocontractural Ehlers-Danlos Syndrome (former EDS type VIB) and adducted thumb clubfoot syndrome (ATCS) represent a single clinical entity caused by mutations in the dermatan-4-sulfotransferase 1 encoding CHST14 gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Loss of dermatan-4-sulfotransferase 1 function results in adducted thumb-clubfoot syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[IKK1-deficient mice exhibit abnormal development of skin and skeleton.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Knockdown of CITED2 using short-hairpin RNA sensitizes cancer cells to cisplatin through stabilization of p53 and enhancement of p53-dependent apoptosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The relationship between trace elements and cardiac markers in acute coronary syndromes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[N-acetylcysteine and allopurinol synergistically enhance cardiac adiponectin content and reduce myocardial reperfusion injury in diabetic rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Utility of troponin I in patients with cocaine-associated chest pain.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effect of very early intravenous streptokinase infusion in patients with evolving myocardial infarction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Increased transglutaminase 2 and GLUT-1 expression in breast tumors not susceptible to chemoprevention with antioxidants.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucleotide microarray.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Increased claudin-4 expression is associated with poor prognosis and high tumour grade in breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Identification of genes potentially involved in the acquisition of androgen-independent and metastatic tumor growth in an autochthonous genetically engineered mouse prostate cancer model.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A total of 139 tagging single nucleotide polymorphisms (SNPs) in 11 candidate genes (IL2, IL21, IL2RA, CLEC2D, CD69, ERBB3, PTPN11, SH2B3, CLEC16A, CIITA, and PTPN2) were genotyped in a case/control study design consisting of Norwegian Addison's disease patients (n = 332) and Norwegian healthy control individuals (n = 1029).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Host cell gene expression during human immunodeficiency virus type 1 latency and reactivation and effects of targeting genes that are differentially expressed in viral latency.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Comparative proteomic analysis between normal skin and keloid scar.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mitochondrial dysregulation of osteoarthritic human articular chondrocytes analyzed by proteomics: a decrease in mitochondrial superoxide dismutase points to a redox imbalance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Sequence variants at the TERT-CLPTM1L locus associate with many cancer types.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Decrease in urinary creatinine in acute kidney injury influences diagnostic value of urinary biomarker-to-creatinine ratio in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Biological qualification of biomarkers of chemical-induced renal toxicity in two strains of male rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[HOXD10, HOXD11, HOXD13, CCL8 and LIM homeobox 2 were highly and exclusively expressed in RA and CLU, sarcoglycan-gamma, GPR64, POU3F3, peroxisome proliferative activated receptor-gamma and tripartite motif-containing 2 were expressed only in OA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Differential regulation of clusterin and its isoforms by androgens in prostate cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Among the total twelve genes, six genes were strongly up- (MT-3, ACAT1, clusterin and ApoE) or down- (ZnT-1 and PRG-3) regulated by developmental seizures (EXP1) compared with that in the CONT1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Chymase is activated in the pulmonary inflammation and fibrosis induced by paraquat in hamsters.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Segregation of a mutation in CNGB1 encoding the beta-subunit of the rod cGMP-gated channel in a family with autosomal recessive retinitis pigmentosa.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Role of cannabinoid type 1 receptors in locomotor activity and striatal signaling in response to psychostimulants.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Anandamide mediates hyperdynamic circulation in cirrhotic rats via CB(1) and VR(1) receptors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A common polymorphism in the cannabinoid receptor 1 (CNR1) gene is associated with antipsychotic-induced weight gain in Schizophrenia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Delta9-tetrahydrocannabinol inhibits cell cycle progression in human breast cancer cells through Cdc2 regulation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Antifibrogenic role of the cannabinoid receptor CB2 in the liver.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Cannabinoids ameliorate pain and reduce disease pathology in cerulein-induced acute pancreatitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Thus, we conclude that CNTF acts as a modifier gene that leads to early onset of disease in patients with FALS who have SOD-1 mutations, in patients with sporadic amyotrophic lateral sclerosis, and in the hSOD-1G93A mouse model.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Disruption of contactin 4 (CNTN4) results in developmental delay and other features of 3p deletion syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[At a gene level, CAM genes associated in all three samples (NRXN1 and CNTNAP2), which were previously implicated in specific language disorder, autism and schizophrenia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Deletion of 7q34-q36.2 in two siblings with mental retardation, language delay, primary amenorrhea, and dysmorphic features.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Usefulness of carvedilol in the treatment of chronic aortic valve regurgitation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Poor maternal nutrition leads to alterations in oxidative stress, antioxidant defense capacity, and markers of fibrosis in rat islets: potential underlying mechanisms for development of the diabetic phenotype in later life.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Oral submucous fibrosis: review on aetiology and pathogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Hepatocellular carcinoma-associated protein markers investigated by MALDI-TOF MS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genome-wide association for methamphetamine dependence: convergent results from 2 samples.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Influence of heme oxygenase 1 modulation on the progression of murine collagen-induced arthritis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Investigate pathogenic mechanism of TXNDC5 in rheumatoid arthritis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[CGIs in putative promoter regions of 34 genes (ABHD9, BARHL1, CLIC5, CNNM1, COL2A1, CPT1C, DDIT4L, DERL3, DHRS3, DPYS, EFEMP2, FAM62C, FAM78A, FLJ33790, GBX2, GPR10, GPRASP1, HOXA9, HOXD11, HOXD12, HOXD13, p14ARF, PAX6, PRDX2, PTPRG, RASD1, RAX, REC8L1, SLC27A3, TGFB2, TLX2, TMEM22, TMEM30B, and UNC5C) were found to be methylated in at least 1 of 13 melanoma cell lines but not in two cultured normal melanocytes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[We have identified a novel COL2A1 mutation at a splice-acceptor site within intron 10 (c.709-2A>G) in an OSMED patient.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Monitoring patients on methotrexate: hepatic fibrosis not seen in patients with normal serum assays of aminoterminal peptide of type III procollagen.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Renoprotective effects of carvedilol in hypertensive-stroke prone rats may involve inhibition of TGF beta expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The value of amino-terminal propeptide of type III procollagen in routine screening for methotrexate-induced liver fibrosis: a 10-year follow-up.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effect of combination therapy with enalapril and the TGF-beta antagonist 1D11 in unilateral ureteral obstruction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Protective effects of blocking renin-angiotensin system on the progression of renal injury in glomerulosclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Renal extracellular matrix accumulation in acute puromycin aminonucleoside nephrosis in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A mutation in COL9A1 causes multiple epiphyseal dysplasia: further evidence for locus heterogeneity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Our data implicate COMMD1 in the pathogenesis of WD and indicate that COMMD1 exerts its regulatory role in copper homeostasis through the regulation of ATP7B stability.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Our data demonstrate that PSACH and some forms of MED are allelic and suggest an essential role for Ca++ binding in COMP structure and function.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[About one-third of PSACH cases result from heterozygosity for deletion of one codon within a very short triplet repeat, (GAC)5, which encodes five consecutive aspartic acid residues within the calmodulin-like region of the COMP protein.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Association between the catechol-O-methyltransferase Val158Met polymorphism and cocaine dependence.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Association of codon 108/158 catechol-O-methyltransferase gene polymorphism with the psychiatric manifestations of velo-cardio-facial syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Nuclear receptor, coregulator signaling, and chromatin remodeling pathways suggest involvement of the epigenome in the steroid hormone response of endometrium and abnormalities in endometriosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Methylation silencing of angiopoietin-like 4 in rat and human mammary carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Prediction of sensitivity of advanced non-small cell lung cancers to gefitinib (Iressa, ZD1839).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Ameliorating effect of Kalpaamruthaa, a Siddha preparation in adjuvant induced arthritis in rats with reference to changes in proinflammatory cytokines and acute phase proteins.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Ceruloplasmin alters the tissue disposition and neurotoxicity of manganese, but not its loading onto transferrin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Aceruloplasminemia, an inherited disorder of iron metabolism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genomic and epigenomic integration identifies a prognostic signature in colon cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The carboxypeptidase E knockout mouse exhibits endocrinological and behavioral deficits.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[We measured the expression of three synaptic proteins (synaptophysin, complexin I and complexin II) in the cerebellar cortex of 16 subjects with schizophrenia and 16 controls using in situ hybridisation histochemistry and immunoautoradiography.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A proteomic analysis of liver mitochondria during acute endotoxemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Molecular and clinical analyses of Japanese patients with carbamoylphosphate synthetase 1 (CPS1) deficiency.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Carbamyl phosphate synthetase I deficiency. One base substitution in an exon of the CPS I gene causes a 9-basepair deletion due to aberrant splicing.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Identification of fibrosis-relevant proteins using DIGE (difference in gel electrophoresis) in different models of hepatic fibrosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Neonatal pulmonary hypertension--urea-cycle intermediates, nitric oxide production, and carbamoyl-phosphate synthetase function.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Real-time quantitative PCR assays in white blood cells indicated decreased CPT1B and CHKB expression in subjects with the C allele, suggesting that a genetic variant regulating CPT1B or CHKB expression is associated with narcolepsy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[We also replicated previous associations at CR1 (rs6701713; P(M) = 4.6 10(-10), P(J) = 5.2 10(-11)), CLU (rs1532278; P(M) = 8.3 10(-8), P(J) = 1.9 10(-8)), BIN1 (rs7561528; P(M) = 4.0 10(-14), P(J) = 5.2 10(-14)) and PICALM (rs561655; P(M) = 7.0 10(-11), P(J) = 1.0 10(-10)), but not at EXOC3L2, to late-onset Alzheimer's disease susceptibility.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Cellular retinoic acid binding protein I: expression and functional influence in renal cell carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Multiple genes exhibit phenobarbital-induced constitutive active/androstane receptor-mediated DNA methylation changes during liver tumorigenesis and in liver tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Resistance to all-trans retinoic acid (ATRA) therapy in relapsing acute promyelocytic leukemia: study of in vitro ATRA sensitivity and cellular retinoic acid binding protein levels in leukemic cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[We mapped a high-penetrance gene (CRAC1; also known as HMPS) associated with colorectal cancer (CRC) in the Ashkenazi population to a 0.6-Mb region on chromosome 15 containing SCG5 (also known as SGNE1), GREM1 and FMN1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Following the improvement of cardiac function and ventricular remodeling, ICER and CREB mRNA in pre- and post- myocardial-infarction groups were down-regulated, and phosphodiesterase 3A and Bcl-2 mRNA were up-regulated (P<0.05).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The mutational landscape of adenoid cystic carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The androgen receptor co-activator CBP is up-regulated following androgen withdrawal and is highly expressed in advanced prostate cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The neurosteroid tetrahydroprogesterone counteracts corticotropin-releasing hormone-induced anxiety and alters the release and gene expression of corticotropin-releasing hormone in the rat hypothalamus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Chest pain after intravenous corticotropin-releasing hormone.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Heart rate dynamics and behavioral responses during acute emotional challenge in corticotropin-releasing factor receptor 1-deficient and corticotropin-releasing factor-overexpressing mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A comparative study of the antipyretic effects of indomethacin and dipyrone in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Attenuation of corticotropin releasing factor-induced hypotension in anesthetized rats with the CRF antagonist, alpha-helical CRF9-41; comparison with effect on ACTH release.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[This is the first case to demonstrate that CRH administration can induce pituitary apoplexy in a patient with Cushing's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Increased expression of gamma-aminobutyric acid transporter-1 in the forebrain of infant rats with corticotropin-releasing hormone-induced seizures but not in those with hyperthermia-induced seizures.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Corticotropin-releasing factor (CRF) injected into the cerebral ventricles of small mammals induces EEG limbic seizures, behavioral excitability, stereotyped behavior, and tardive enhancement of hippocampal theta voltage and frequency.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Corticotropin-releasing hormone (CRH) administered into the cerebral ventricles of rats during the first postnatal week caused a specific and stereotyped behavior sequence: rhythmic chewing and licking (jaw myoclonus) were followed by 'limbic'-type seizures.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[C-Fos expression as a molecular marker in corticotropin-releasing factor-induced seizures.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[To investigate the pathophysiology of infantile spasms (IS), we measured the cerebrospinal fluid (CSF) levels of beta-endorphin (beta-EP), adrenocorticotropic hormone (ACTH), and corticotropin-releasing hormone (CRH) in 20 patients with IS, including 11 with the secondary form and 9 with the cryptogenic form of the disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Corticotropin-releasing factor-binding protein ligand inhibitor blunts excessive weight gain in genetically obese Zucker rats and rats during nicotine withdrawal.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Corticotropin-releasing factor receptor type 1 is involved in the stress-induced exacerbation of chronic contact dermatitis in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Prenatal retinoic acid treatment upregulates late gestation lung protein 1 in the nitrofen-induced hypoplastic lung in late gestation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Intractable insomnia after cessation of treatment with thalidomide.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Antioxidant potential, paraoxonase 1, ceruloplasmin activity and C-reactive protein concentration in diabetic retinopathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Elevation of C-reactive protein (CRP) levels in blood was recognized as one of the cardiac disease risk factors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Serum C-reactive protein concentrations in cyclosporine-treated renal allograft recipients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effectiveness of the concomitant use of bivalirudin and drug-eluting stents (from the prospective, multicenter BivAlirudin and Drug-Eluting STents [ADEST] study).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[C-reactive protein and haptoglobin in the evaluation of a community-based malaria control programme.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[We evaluated the association between a persistent elevation of C-reactive protein (CRP) level and the presence or severity of ischemic heart disease (IHD) in patients with continuous ambulatory peritoneal dialysis (CAPD).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Eosinophil counts should not be relied on for diagnosis of clozapine-related myocarditis, but elevated CRP may be an early indicator of developing myocarditis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effect of Mannheimia (Pasteurella) haemolytica infection on acute-phase proteins and some mineral levels in colostrum-breast milk-fed or colostrum-breast milk-deprived sheep.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Leber congenital amaurosis caused by a homozygous mutation (R90W) in the homeodomain of the retinal transcription factor CRX: direct evidence for the involvement of CRX in the development of photoreceptor function.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Comparative proteomic analysis of esophageal squamous cell carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Pharmacogenomic profiling of an oxidative stress-mediated spongiform encephalopathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Global analysis of differentially expressed genes in androgen-independent prostate cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Posttranslational modification of differentially expressed mitochondrial proteins in the retina during early experimental autoimmune uveitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A 5-base insertion in the gammaC-crystallin gene is associated with autosomal dominant variable zonular pulverulent cataract.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A 6-bp deletion in the Crygc gene leading to a nuclear and radial cataract in the mouse.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Orchestrated downregulation of genes involved in oxidative metabolic pathways in obese vs. lean high-fat young male consumers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genome-wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget's disease of bone.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[c-fms is present in primary tumours as well as in their metastases in bone marrow.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Phase I and pharmacokinetic study of recombinant human granulocyte-macrophage colony-stimulating factor given in combination with fluorouracil plus calcium leucovorin in metastatic gastrointestinal adenocarcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[GM-CSF in busulfan overdosage.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Patients with acute VL as well as VL patients receiving sodium stibogluconate treatment displayed significantly increased levels of PEG precipitate-induced GM-CSF.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Combination therapy with GM-CSF and IL-12 represents a promising immunotherapy strategy for treating orthotopic, widespread liver tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[DICE (dexamethasone, ifosfamide, cisplatin, etoposide) infusional chemotherapy for refractory or relapsed non-Hodgkin's lymphoma (NHL).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A prospective randomized phase II trial of GM-CSF priming to prevent topotecan-induced neutropenia in chemotherapy-naive patients with malignant melanoma or renal cell carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Severe atypical neuropathy associated with administration of hematopoietic colony-stimulating factors and vincristine.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[With GM-CSF starting on day 1, dose-limiting granulocytopenia occurred during cycle no.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Dapsone-induced agranulocytosis. The role of xenobiotic-metabolizing enzymes demonstrated by a case report].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Alternating dose-dense chemotherapy in patients with high volume disseminated non-seminomatous germ cell tumours.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Methimazole-induced aplastic anemia].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Ticlopidine-induced aplastic anemia and quick recovery with G-CSF: case report and literature review.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[High-dose paclitaxel with granulocyte colony-stimulating factor in patients with advanced breast cancer refractory to anthracycline therapy: a European Cancer Center trial.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Phase I and pharmacologic study of paclitaxel and cisplatin with granulocyte colony-stimulating factor: neuromuscular toxicity is dose-limiting.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Significant activity of paclitaxel in advanced transitional-cell carcinoma of the urothelium: a phase II trial of the Eastern Cooperative Oncology Group.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Granulocyte colony-stimulating factor improves left ventricular function of doxorubicin-induced cardiomyopathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Intermittent dosing of G-CSF to ameliorate carbon tetrachloride-induced liver fibrosis in mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Weekly cisplatin, epirubicin, and paclitaxel with granulocyte colony-stimulating factor support vs triweekly epirubicin and paclitaxel in locally advanced breast cancer: final analysis of a sicog phase III study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Phase II trial of paclitaxel in patients with soft-tissue sarcoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[By contrast, two patients who received G-CSF with 30 mg/kg of VP-16 developed hyperbilirubinemia and veno-occlusive disease, which terminated this phase I study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Fludarabine + Ara-C + G-CSF: cytotoxic effect and induction of apoptosis on fresh acute myeloid leukemia cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Primary systemic chemotherapy with sequential, dose-dense epirubicin and docetaxel for inoperable, locally advanced inflammatory breast cancer: a phase II study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Protective role of granulocyte colony-stimulating factor against adriamycin induced cardiac, renal and hepatic toxicities.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[High dose cyclophosphamide plus recombinant human granulocyte-colony stimulating factor (rhG-CSF) in the treatment of follicular, low grade non-Hodgkin's lymphoma: CALGB 9150.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A patient under Taxol and granulocyte colony stimulating factor (G-CSF, Neupogen) treatment for metastatic breast carcinoma of the liver experienced repeated suicidal depression on days 10 and 11 of therapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Intricate dose-response surfaces of the effects of the different treatments on colony-forming units-erythroid, reticulocytes, hematocrit, colony-forming units-granulocyte/macrophage, and absolute neutrophil count were obtained, which revealed that: (a) simultaneous EPO administration was able to maintain reticulocyte production and to protect mice from VP-16 induced anemia; (b) simultaneous G-CSF administration was able to maintain granulocyte production and to protect mice from VP-16 induced neutropenia; (c) VP-16 dose escalation was feasible when EPO or G-CSF were simultaneously administered; and (d) no increased myelotoxicity on erythroid or granuloid progenitors was observed when EPO or G-CSF was simultaneously administered with VP-16.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Docetaxel and epirubicin supported by granulocyte colony-stimulating factor first-line in advanced breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Single-agent thalidomide for advanced and refractory multiple myeloma].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Combined administration of G-CSF and dexamethasone for the mobilization of granulocytes in normal donors: optimization of dosing.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Astemizole in the treatment of granulocyte colony-stimulating factor-induced bone pain.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Two cycles of combination chemotherapy followed by granulocyte colony-stimulating factor (G-CSF) were given at a dose of etoposide (500 mg/m2), ifosfamide (4000 mg/m2), cisplatin (50 mg/m2), and epirubicin (50 mg/m2) to 100 consecutive patients with SCLC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Characterization of genomic variants in CSH1 and GH2, two candidate genes for Silver-Russell syndrome in 17q24-q25.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Carcinomas showed relatively high expression of several genes associated with mammary epithelial cell growth and proliferation (e.g., cyclin D1, PDGFalpha) and relatively low expression of differentiation marker genes (e.g., beta -casein, whey acidic protein, transferrin).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A zebrafish screen for craniofacial mutants identifies wdr68 as a highly conserved gene required for endothelin-1 expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Arsenic-induced malignant transformation of human keratinocytes: involvement of Nrf2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Hormonally active doses of isoflavone aglycones promote mammary and endometrial carcinogenesis and alter the molecular tumor environment in Donryu rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Microarray comparison of prostate tumor gene expression in African-American and Caucasian American males: a pilot project study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Cystatin C inhibits amyloid-beta deposition in Alzheimer's disease mouse models.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Cystatin C has been accepted to be a significant prognostic factor for cardiovascular diseases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Ameliorative effects of SLC22A2 gene polymorphism 808 G/T and cimetidine on cisplatin-induced nephrotoxicity in Chinese cancer patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[In the clinical samples of meningioma, the levels of cathepsins B and L, stefin B, and cystatin C were highest in the tumors of higher histological grades, whereas stefin A and progesterone receptor were the only markers that were significantly increased and decreased, respectively, in WHO Grade III lesions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Of note, the known tumor invasiveness marker cathepsin B, measured in whole-tumor homogenates, was not prognostic, in contrast to its endogenous inhibitor stefin B, which was highly significant and the only independent prognostic factor to predict meningioma relapse in multivariate analysis and reported herein for the first time.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mutations in CTC1, encoding conserved telomere maintenance component 1, cause Coats plus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[We conclude that CT-1 is a master regulator of fat and glucose metabolism with potential applications for treatment of obesity and insulin resistance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The aim of this study was to investigate the expression and distribution pattern of connective tissue growth factor (CTGF) in lung development during different stages, and to compare with a model of stimulated lung growth after tracheal ligation (TL) and with the teratogen model of induced congenital diaphragmatic hernia (CDH) and lung hypoplasia after nitrofen.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effects of yishen huoxue decoction on proliferating cell nuclear antigen expression and extracellular matrix in 5/6 nephrectomized rats].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The expression of CTGF was increased in the cardiomyocyte of young rats with HF and benazepril could prevent left ventricular from remodeling partly and improve cardiac function by inhibiting the expression of CTGF in cardiomyocyte in cases of HF.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Connective tissue growth factor (CTGF) and persistent myofibroblast formation are major determinants of the aggressive fibrotic disease, idiopathic pulmonary fibrosis (IPF).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A genome-wide association study identifies two new risk loci for Graves' disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[More frequent beta-catenin gene mutations in adenomas than in aberrant crypt foci or adenocarcinomas in the large intestines of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-treated rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Relationship of beta-catenin and Bcl-2 expression to sulindac-induced regression of intestinal tumors in Min mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Frequent mutations of the Trp53, Hras1 and beta-catenin (Catnb) genes in 1,3-butadiene-induced mammary adenocarcinomas in B6C3F1 mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Gene expression and mutation assessment provide clues of genetic and epigenetic mechanisms in liver tumors of oxazepam-exposed mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Characterization of dysplastic aberrant crypt foci in the rat colon induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[High frequency of beta-catenin (ctnnb1) mutations in the colon tumors induced by two heterocyclic amines in the F344 rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Proteomic analysis of intestinal epithelial cells expressing stabilized beta-catenin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Tumor formation in liver of conditional -catenin-deficient mice exposed to a diethylnitrosamine/phenobarbital tumor promotion regimen.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mutation of beta-catenin is an early event in chemically induced mouse hepatocellular carcinogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effect of downregulated -catenin on cell proliferative activity, the sensitivity to chemotherapy drug and tumorigenicity of ovarian cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Inactivation of Apc in the mouse prostate causes prostate carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[In CTNNB1-mutated hepatoblastoma, expression of GS was only detected in tumour areas with epithelial, not with mesenchymal differentiation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Comparative proteomic profiles of the hepatopancreas in Fenneropenaeus chinensis response to hypoxic stress.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Differential protein profiling in renal-cell carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[These findings provide evidence that PLS and HMS are allelic variants of cathepsin C gene mutations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Papillon-Lefvre syndrome treated with acitretin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The lower abundance of cathepsin D protein in RA compared to OA tissue was also reproduced in other patient samples.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Resveratrol enhances anti-proliferative effect of VACM-1/cul5 in T47D cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Involvement of T helper 17 cells in D-penicillamine-induced autoimmune disease in Brown Norway rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORt cells in allergic inflammation, local lung distribution and chemokine gene expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effect of furosemide infusion on renal hemodynamics and angiogenesis gene expression in acute renal ischemia/reperfusion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Superoxide dismutase 1 overexpression reduces MCP-1 and MIP-1 alpha expression after transient focal cerebral ischemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Serum levels of monokine-induced by interferon-gamma (IFN-gamma) (MIG/CXCL9), IFN-gamma-inducible protein-10 (IP-10/CXCL10), and IFN-gamma-inducible T cell alpha chemoattractant (I-TAC/CXCL11) were elevated in patients with IC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Gene expression profiling of early primary biliary cirrhosis: possible insights into the mechanism of action of ursodeoxycholic acid.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Discrimination of tumorigenic triazole conazoles from phenobarbital by transcriptional analyses of mouse liver gene expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Reduced expression of lipopolysaccharide-induced CXC chemokine in Porphyromonas gingivalis-induced experimental periodontitis in matrix metalloproteinase-8 null mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Glioblastoma and endothelial cells cross-talk, mediated by SDF-1, enhances tumour invasion and endothelial proliferation by increasing expression of cathepsins B, S, and MMP-9.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[This is the first report showing that CXCL12 G801A polymorphism may be a risk factor for PC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Molecular evidence for differences in endometrium in severe versus mild endometriosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Detection of differentially expressed genes in synovial fibroblasts by restriction fragment differential display.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[CXCL2 mediates lipopolysaccharide-induced osteoclastogenesis in RANKL-primed precursors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[ERE-independent ERalpha target genes differentially expressed in human breast tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Milano summer particulate matter (PM10) triggers lung inflammation and extra pulmonary adverse events in mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Expression profiling and identification of novel genes in hepatocellular carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Down-regulation of CXCR2 on neutrophils in severe sepsis is mediated by inducible nitric oxide synthase-derived nitric oxide.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[In the kidney, expression of the CXCR3 receptor and its ligands is up-regulated in states of glomerulonephritis and in allograft rejection, but little is known about the expression and functional role the CXCR3 receptor might play.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The influence of intraoperative pleural perfusion with matrine-cisplatin or cisplatin on stromal cell-derived factor-1 in non-small cell lung cancer patients with subclinical pleural metastasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Examination of published literature revealed point mutations in DIA1R are associated with X-linked mental retardation (XLMR) and DIA1R deletion is associated with syndromes with ASD-like traits and/or XLMR.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effects of paricalcitol and enalapril on atherosclerotic injury in mouse aortas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Vascular NADH oxidase is involved in impaired endothelium-dependent vasodilation in OLETF rats, a model of type 2 diabetes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Human neutrophil cytochrome b light chain (p22-phox). Gene structure, chromosomal location, and mutations in cytochrome-negative autosomal recessive chronic granulomatous disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Contribution of reactive oxygen species to the pathogenesis of left ventricular failure in Dahl salt-sensitive hypertensive rats: effects of angiotensin II blockade.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Niacin ameliorates oxidative stress, inflammation, proteinuria, and hypertension in rats with chronic renal failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Protection of podocytes from hyperhomocysteinemia-induced injury by deletion of the gp91phox gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Heterozygous mutation in the cholesterol side chain cleavage enzyme (p450scc) gene in a patient with 46,XY sex reversal and adrenal insufficiency.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Conversely, inhibition of neurosteroid synthesis accelerated the onset of spontaneous seizures, but only in animals exhibiting significant increases in P450scc.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Chemopreventive actions by enterolactone and 13 VIOXX-related lactone derivatives in H295R human adrenocortical carcinoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[In this molecular epidemiological study, we used logistic regression to compare the genotype frequencies of estrogen-metabolizing genes that are involved in estrogen biogenesis (CYP17), hydroxylation (CYP1A1) and inactivation of the reactive metabolites (catechol-O-methyltransferase, COMT) in HCC patients and control subjects, and determined their relationship with the risk of female HCC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Malignant arterial hypertension disclosing late congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Congenital hypopituitarism as a cause of undetectable estriol levels in the maternal triple-marker screen.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[For single polymorphisms, the presence of Y alleles showed a significantly lower risk of prostate cancer in comparison with the D/D genotype in UGT2B15 (odds ratio [OR]=0.41, 95% confidence interval [CI]=1.40-4.28, p=0.0015), and the presence of A2 alleles showed a weak tendency to decrease prostate cancer risk in comparison with the A1/A1 genotype in CYP17 (OR=0.69, 95% CI=0.39-1.23, p=0.21).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Haploinsufficiency of cytochrome P450 17alpha-hydroxylase/17,20 lyase (CYP17) causes infertility in male mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Subsequent logistic regression analysis indicated that 10 SNPs (rs2070744 of NOS3, rs720321 of BCL2, rs17757541 of BCL2, rs11775256 of TNFRSF10A, rs1035142 of CASP8, rs2236302 of MMP14, rs4740363 of ABL1, rs696217 of GHRL, rs2445762 of CYP19A1, and rs11941492 of VEGFR2/KDR) were significantly associated with early onset of EA (55 vs >55 years, all P < .05 after adjusting for co-variates and false discovery rate).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Associations between aromatase CYP19 rs10046 polymorphism and breast cancer risk: from a case-control to a meta-analysis of 20,098 subjects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Relaxin and castration in male mice protect from, but testosterone exacerbates, age-related cardiac and renal fibrosis, whereas estrogens are an independent determinant of organ size.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Dysfunction of the enzyme aromatase (CYP19) is associated with endocrine pathologies such as osteoporosis, impaired fertility and development of hormone-dependent cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The expression of sex steroid synthesis and inactivation enzymes in subcutaneous adipose tissue of PCOS patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Aromatase deficiency in a female who is compound heterozygote for two new point mutations in the P450arom gene: impact of estrogens on hypergonadotropic hypogonadism, multicystic ovaries, and bone densitometry in childhood.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The CYP1A1*2A polymorphism was found to have significant association with chronic obstructive pneumonopathy (p=0.045), peripheral circulatory problems (trend p=0.042), arteritis (p=0.022), allergies (trend p=0.046), hemorrhoids (trend p=0.026), allergic dermatitis (p=0.0016) and miscarriages (p=0.012).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Study on serum organochlorines pesticides (DDTs) level, CYP1A1 genetic polymorphism and risk of breast cancer: a case control study].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Polymorphisms of estrogen-metabolizing genes and risk of hepatocellular carcinoma in Taiwan females.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[In utero and lactational exposure to a complex mixture of polychlorinated biphenyls: toxicity in pups dependent on the Cyp1a2 and Ahr genotypes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Autoprotection against acetaminophen toxicity in cultured rat hepatocytes: the effect of pretreatment and growth factors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Moreover, a significant increase in the risk to SCC of lung in the cases carrying combination of variant genotype of CYP1A2 with either CYP1A1 or GSTM1 have shown that gene-gene interactions may play an important role in squamous cell lung cancer risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Caffeine, selected metabolic gene variants, and risk for neural tube defects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Association between CYP1A2 polymorphism and susceptibility to porphyria cutanea tarda.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Understanding the role of xenobiotic-metabolism in chemical carcinogenesis using gene knockout mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[This study was aimed at validating the use of CYP1B1 as a target for the prodrug therapy in OSCC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[While investigating the above finding, we found that expression of CYP26A1, a major retinoic acid catabolic enzyme, was up-regulated in Apc(MIN) mouse adenomas, human FAP adenomas, human sporadic colon carcinomas, and in the intestine of apc(mcr) mutant zebrafish embryos.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A potential role for sterol 27-hydroxylase in atherogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Patients with inherited `cerebrotendinous xanthomatosis` lack sterol 27-hydroxylase (CYP27A1) and develop severe premature atherosclerosis despite normal serum cholesterol concentrations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[CYP2A6 and ERCC1 polymorphisms correlate with efficacy of S-1 plus cisplatin in metastatic gastric cancer patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Frequency of CYP2A6 gene deletion and its relation to risk of lung and esophageal cancer in the Chinese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[In HBV-infected liver, double immunostaining revealed that overexpression of CYP2A6 occurred in hepatocytes expressing the HBV core antigen.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Acute kidney injury in patients with inactive cytochrome P450 polymorphisms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Patients who were either heterozygous or homozygous for CYP2C19*2 had a significantly lower risk of developing premature ovarian failure (relative risk 0.10; 95% confidence interval 0.02-0.52), after adjustment for age and total number of cyclophosphamide pulses received.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Leflunomide-induced acute hepatitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effects of CYP inhibitors on precocene I metabolism and toxicity in rat liver slices.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genetic polymorphism of the human cytochrome P450 2C9 gene and its clinical significance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Association of CYP2C9 gene polymorphism with bleeding as a complication of warfarin therapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Recurrent thromboses and hemorrhagic complications in patients with antiphospholipid syndrome during therapy with warfarin plus aspirin].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genetic susceptibility to nonsteroidal anti-inflammatory drug-related gastroduodenal bleeding: role of cytochrome P450 2C9 polymorphisms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Delirium resolving upon switching from risperidone to quetiapine: implication of CYP2D6 genotype.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Cytochrome oxidase 2D6 gene polymorphism in primary open-angle glaucoma with various effects to ophthalmic timolol.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Prevalent breast cancer patients with a homozygous mutant status for CYP2D6*4: response and biomarkers in tamoxifen users.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Impact of CYP2D6*10 on H1-antihistamine-induced hypersomnia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Hepatic effects of a methionine-choline-deficient diet in hepatocyte RXRalpha-null mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Association between restriction fragment length polymorphism of the human cytochrome P450IIE1 gene and susceptibility to lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[CYP3A4 polymorphisms--potential risk factors for breast and prostate cancer: a HuGE review.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Overexpression of cytochrome P-450 isoforms involved in aflatoxin B1 bioactivation in human liver with cirrhosis and hepatitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Increased risk of vincristine neurotoxicity associated with low CYP3A5 expression genotype in children with acute lymphoblastic leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Organic anion transporting polypeptide 1a1 null mice are sensitive to cholestatic liver injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genetic and ethnic risk factors associated with drug hypersensitivity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Enhanced fracture repair by leukotriene antagonism is characterized by increased chondrocyte proliferation and early bone formation: a novel role of the cysteinyl LT-1 receptor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The cysteinyl leukotriene receptor 2 (CYSLTR2) gene on chromosome 13q14.12-q21.1 encodes a receptor for CYSLTs, potent biological mediators in the pathogenesis of asthma, particularly that associated with aspirin intolerance (AIA).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Epigenetic changes in therapy-related MDS/AML.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[To verify the participation of DAPK1 silencing in cerebral invasion, we analyzed its promoter methylation status in a series of 28 samples from cerebral metastases using MSP and sequencing of the MSP-product.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genes associated with early development, apoptosis and cell cycle regulation define a gene expression profile of adenoid cystic carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Dopamine beta-hydroxylase (DBH) gene and schizophrenia phenotypic variability: a genetic association study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Epigenetic down-regulation and suppressive role of DCBLD2 in gastric cancer cell proliferation and invasion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Evaluation of plasma carcinogenic markers in rat hepatic tumors models induced by rat hepatoma N1-S1 cells and benzo[a]pyrene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Unique transcriptome, pathways, and networks in the human endometrial fibroblast response to progesterone in endometriosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genome-wide association identifies three new susceptibility loci for Paget's disease of bone.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[DCTN1 mutations in Perry syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Role of nitric oxide-producing and -degrading pathways in coronary endothelial dysfunction in chronic kidney disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[We show that the translocation t(12;16)(q13:p11) in malignant myxoid liposarcoma can be a fusion of the CHOP dominant negative transcription factor gene with a novel gene, FUS, which can result in fusion of the FUS glycine-rich protein with the whole CHOP coding region.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[CHOP was weakly expressed in podocytes of control kidneys but up-regulated in most proteinuric human kidneys and in rat puromycin nephrosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Pharmacologic targeting or genetic deletion of mitochondrial cyclophilin D protects from NSAID-induced small intestinal ulceration in mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Taken together, our data suggest that RTP801 is an important RA-regulated gene involved in myeloid differentiation, which could represent a therapeutic target in leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Increased susceptibility of Huh7 cells to HCV replication does not require mutations in RIG-I.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Differential labeling by monoclonal antibodies Adnab-9 and anti-alpha-defensin 5 based on the distribution and adenomatous tissue content of colonic polyps.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Single nucleotide polymorphisms in human Paneth cell defensin A5 may confer susceptibility to inflammatory bowel disease in a New Zealand Caucasian population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Altered expression of innate immunity genes in different intestinal sites of children with ulcerative colitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[To gain insight into the role of IF proteins in podocytes, we investigated the expression of nestin, vimentin, and desmin in puromycin aminonucleoside (PAN) nephrosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Apoptosis in acquired and genetic hearing impairment: the programmed death of the hair cell.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Smith-Lemli-Opitz syndrome (SLOS) is attributable to mutations in the gene coding for 7-dehydrocholesterol reductase.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A patient with Smith-Lemli-Opitz syndrome: novel mutation of the DHCR7 gene and effects of therapy with simvastatin and cholesterol supplement.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Variance in the expression of 5-Fluorouracil pathway genes in colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Dihydrofolate reductase deficiency due to a homozygous DHFR mutation causes megaloblastic anemia and cerebral folate deficiency leading to severe neurologic disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Altered expression of DHFR and RFC1 is a feasible mechanism by which osteosarcoma cells become resistant to methotrexate.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Sensitization of TRAIL-resistant LNCaP cells by resveratrol (3, 4', 5 tri-hydroxystilbene): molecular mechanisms and therapeutic potential.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Euthyroid hyperthyroxinemia due to a generalized 5'-deiodinase defect.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Gene expression profiles of hepatic cell-type specific marker genes in progression of liver fibrosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[DISC1 duplication in two brothers with autism and mild mental retardation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[X-linked DC is due to mutations in DKC1, while heterozygous mutations in TERC (telomerase RNA component) and TERT (telomerase reverse transcriptase) have been found in autosomal dominant DC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Identification of ATF-3, caveolin-1, DLC-1, and NM23-H2 as putative antitumorigenic, progesterone-regulated genes for ovarian cancer cells by gene profiling.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Craniofacial dysmorphogenesis including cleft palate in mice with an insertional mutation in the discs large gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The study provides an initial link between human DLG4 gene variation and key neural endophenotypes of Williams' syndrome and perhaps corticoamygdala regulation of emotional and social processes more generally.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mapping of the autosomal recessive (AR) craniometaphyseal dysplasia locus to chromosome region 6q21-22 and confirmation of genetic heterogeneity for mild AR spondylocostal dysplasia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Common genetic variation in the GAD1 gene and the entire family of DLX homeobox genes and autism spectrum disorders.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[As a result of their ability to induce translational readthrough of stop codons, the aminoglycoside antibiotics are currently being tested for efficacy in the treatment of Duchenne muscular dystrophy patients carrying a nonsense mutation in the dystrophin gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Gentamicin treatment of Duchenne and Becker muscular dystrophy due to nonsense mutations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mutations in the dystrophin gene causing Duchenne's muscular dystrophy (DMD) lead to premature stop codons.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mutations in the dystrophin gene that lead to the expression of truncated forms of the dystrophin protein cause muscular dystrophies of varying severities both in humans and in mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Duchenne muscular dystrophy (DMD) is a fatal disease of striated muscle deterioration resulting from the loss of the cytoskeletal protein dystrophin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Antisense PMOs, the effectiveness of which has been demonstrated in a dog model, achieved multi-exon skipping of dystrophin gene on the FACS-aided MyoD-transduced fibroblasts from an exon 7-deleted DMD patient, suggesting the feasibility of systemic multi-exon skipping in humans.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mutations affecting the cytoplasmic functions of the co-chaperone DNAJB6 cause limb-girdle muscular dystrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Epigenetic silencing of novel tumor suppressors in malignant melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Silencing of renal DNaseI in murine lupus nephritis imposes exposure of large chromatin fragments and activation of Toll like receptors and the Clec4e.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A lethal defect of mitochondrial and peroxisomal fission.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Here we show that mutations in DNMT1 cause both central and peripheral neurodegeneration in one form of hereditary sensory and autonomic neuropathy with dementia and hearing loss.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of DNA methyltransferases 1 and 3a.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Hematopoietic stem cell transplantation corrects the immunologic abnormalities associated with immunodeficiency-centromeric instability-facial dysmorphism syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Dedicator of cytokinesis 8 is disrupted in two patients with mental retardation and developmental disabilities.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Renal dipeptidylpeptidase IV excretion in drug-induced kidney changes].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Structural variation of chromosomes in autism spectrum disorder.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Dipeptidyl peptidase II and leukocyte cell death.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase expression in colorectal cancer and normal mucosa in patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[DPD is a molecular determinant of capecitabine efficacy in colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Thymidylate synthase, dihydropyrimidine dehydrogenase, orotate phosphoribosyltransferase mRNA and protein expression levels in solid tumors in large scale population analysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Dihydropyrimidine dehydrogenase deficiency presenting at birth.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Hemizygous deletions on chromosome 1p21.3 involving the DPYD gene in individuals with autism spectrum disorder.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Pyrimidine degradation defects and severe 5-fluorouracil toxicity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genetic inactivation of dopamine D1 but not D2 receptors inhibits L-DOPA-induced dyskinesia and histone activation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Hypotensive and bradycardic effects elicited by spinal dopamine receptor stimulation: effects of D1 and D2 receptor agonists and antagonists.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[D1/D2 dopamine and N-methyl-D-aspartate (NMDA) receptor participation in experimental catalepsy in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Dopamine D1- and D2-like receptor mechanisms in relapse to cocaine-seeking behavior: effects of selective antagonists and agonists.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Relapse to cocaine- and heroin-seeking behavior mediated by dopamine D2 receptors is time-dependent and associated with behavioral sensitization.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Cocaine dependence and d2 receptor availability in the functional subdivisions of the striatum: relationship with cocaine-seeking behavior.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effects of extended access to high versus low cocaine doses on self-administration, cocaine-induced reinstatement and brain mRNA levels in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Addiction-related alterations in D1 and D2 dopamine receptor behavioral responses following chronic cocaine self-administration.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[D2R DNA transfer into the nucleus accumbens attenuates cocaine self-administration in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[In the catalepsy test, felbamate antagonized dopamine D2 receptor- but not D1 receptor-induced akinesia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Dopamine D2S and D2L receptors may differentially contribute to the actions of antipsychotic and psychotic agents in mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Thiethylperazine-induced parkinsonism: in vivo demonstration of dopamine D2 receptors blockade.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Subjective experience and striatal dopamine D(2) receptor occupancy in patients with schizophrenia stabilized by olanzapine or risperidone.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Thus, the absence of D2R lowers the threshold for seizures induced by both glutamate and acetylcholine.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Dopamine D1 and D2 receptors mediate opposite functions in seizures induced by lithium-pilocarpine.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Increases in dopamine D3 receptor binding in rats receiving a cocaine challenge at various time points after cocaine self-administration: implications for cocaine-seeking behavior.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Dopamine D3 receptor antagonists improve the learning performance in memory-impaired rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Differential genetic susceptibility in diphasic and peak-dose dyskinesias in Parkinson's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Striatal dopamine d2/d3 receptor availability is reduced in methamphetamine dependence and is linked to impulsivity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effects of oligonucleotide antisense to dopamine D3 receptor mRNA in a rodent model of behavioural sensitization to levodopa.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The DRD5 146-bp (DRD5.146) allele and the DRD4 240-bp (DRD4.240) allele of the promoter polymorphism emerge as the two DNA variants showing a significant association in this large sample of predominantly multiplex families with ADHD, with estimated GRRs of 1.7 and 1.37, respectively.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Association of DRD4 polymorphism with severity of oppositional defiant disorder, separation anxiety disorder and repetitive behaviors in children with autism spectrum disorder.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A polymorphism in the dopamine receptor DRD5 is associated with blepharospasm.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Inhibition of gamma-secretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Only one study reported mutations in DUOX2 gene in congenital hypothyroidism (CH) associated with total iodide organification defect (TIOD) in homozygosity or with partial iodide organification defect (PIOD) in heterozygous patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mutations in TUBG1, DYNC1H1, KIF5C and KIF2A cause malformations of cortical development and microcephaly.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Different transcriptional control of metabolism and extracellular matrix in visceral and subcutaneous fat of obese and rimonabant treated mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Transient arrest in a quiescent state allows ovarian cancer cells to survive suboptimal growth conditions and is mediated by both Mirk/dyrk1b and p130/RB2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Dysferlin is a protein of the sarcolemma that is mutated in patients with limb girdle muscular dystrophy 2B, Miyoshi myopathy, and distal anterior myopathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Our findings have identified, for the first time, novel molecular targets and pathways that led to apoptosis in melanoma cells when Ad-E2F-1 was combined with doxorubicin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Inhibition of 5alpha-reductase enhances testosterone-induced expression of U19/Eaf2 tumor suppressor during the regrowth of LNCaP xenograft tumor in nude mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A loss-of-function mutation in the endothelin-converting enzyme 1 (ECE-1) associated with Hirschsprung disease, cardiac defects, and autonomic dysfunction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Subdepressor dose of benidipine ameliorates diabetic cardiac remodeling accompanied by normalization of upregulated endothelin system in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[We report results of a nonsynonymous SNP scan for ulcerative colitis and identify a previously unknown susceptibility locus at ECM1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Increased plasma endothelin-1 and cardiac nitric oxide during doxorubicin-induced cardiomyopathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Teratogenic effects of blue cohosh (Caulophyllum thalictroides) in Japanese medaka (Oryzias latipes) are probably mediated through GATA2/EDN1 signaling pathway.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The prognostic value of big endothelin-1 in more than 2,300 patients with heart failure enrolled in the Valsartan Heart Failure Trial (Val-HeFT).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Collecting duct-specific knockout of endothelin-1 causes hypertension and sodium retention.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[From the investigation it may be concluded that also patients with uncomplicated essential hypertension without other cardiovascular risk factors or clinical manifestations of atherosclerosis have significantly elevated plasma levels of ICAM-1, vWf and endothelin-1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Patients with uncomplicated hypertension with no other risk factors of atherosclerosis had significantly elevated levels of ICAM-1, vWf, and endothelin-1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Inducible cAMP early repressor (ICER) is a negative-feedback regulator of cardiac hypertrophy and an important mediator of cardiac myocyte apoptosis in response to beta-adrenergic receptor stimulation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Detrimental effects of halothane narcosis on damage after endothelin-1-induced MCAO.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effects of ET-1 on isolated perfused rat liver and vascular rings at two stages of cirrhosis].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Different contributions of endothelin-A and endothelin-B receptors in postischemic cardiac dysfunction and norepinephrine overflow in rat hearts.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Brain insulin-like growth factor and neurotrophin resistance in Parkinson's disease and dementia with Lewy bodies: potential role of manganese neurotoxicity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Endothelin-1, an ulcer inducer, promotes gastric ulcer healing via mobilizing gastric myofibroblasts and stimulates production of stroma-derived factors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effects of endothelin receptor antagonism on acute lung injury induced by chlorine gas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[SO2 inhalation contributes to the development and progression of ischemic stroke in the brain.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Differential roles of peripheral and spinal endothelin receptors in the micturition reflex in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Evidence for antagonistic activity of endothelin for clonidine induced hypotension and bradycardia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mutation of the endothelin-3 gene in the Waardenburg-Hirschsprung disease (Shah-Waardenburg syndrome).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A homozygous mutation in the endothelin-3 gene associated with a combined Waardenburg type 2 and Hirschsprung phenotype (Shah-Waardenburg syndrome).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effects of endothelin 3 on diastolic blood pressure of pithed Sprague-Dawley, Wistar Kyoto, and spontaneously hypertensive rats before and after pretreatment with nifedipine.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Fate of cranial neural crest cells during craniofacial development in endothelin-A receptor-deficient mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Pharmacological inactivation of the endothelin type A receptor in the early chick embryo: a model of mispatterning of the branchial arch derivatives.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Although there was no significant difference in ET(A) mRNA expression between CDH lung with Dex treatment and without Dex treatment, ET(B) mRNA expression was elevated significantly in CDH lung with Dex treatment compared with CDH lung without Dex treatment.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The role of endothelin in experimental cerebral vasospasm.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Sumoylation of eukaryotic elongation factor 2 is vital for protein stability and anti-apoptotic activity in lung adenocarcinoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Comparing the DNA hypermethylome with gene mutations in human colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A potential tumor suppressor role for Hic1 in breast cancer through transcriptional repression of ephrin-A1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Since Efnb1 mutant mice display a spectrum of malformations and an unusual inheritance reminiscent of CFNS, we analyzed the EFNB1 gene in three families with CFNS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mutations of ephrin-B1 (EFNB1), a marker of tissue boundary formation, cause craniofrontonasal syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Progesterone pre-treatment potentiates EGF pathway signaling in the breast cancer cell line ZR-75.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Activation of epidermal growth factor receptor (EGFR)-induced signaling pathway has been correlated with cancer metastasis in various tumors, including breast carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The WT and TGF-alpha (-/-), but not the EGF (-/-) and EGF + TGF-alpha (-/-) fetuses, developed cleft palate after exposure to 24 microg TCDD/kg.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Levels of cytokine in bronchoalveolar lavage (BAL) fluid in patients with pulmonary fibrosis due to sulfur mustard gas inhalation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Co-activation of epidermal growth factor receptor and c-MET defines a distinct subset of lung adenocarcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Dual IHC and FISH testing for ALK gene rearrangement in lung adenocarcinomas in a routine practice: a French study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[We examined epidermal growth factor receptor (EGFR), Kirsten rate sarcoma viral oncogene homolog (KRAS), v-Raf murine sarcoma viral oncogene homolog B1 (BRAF), human epidermal growth factor receptor 2 (HER2), PIK3CA, v-akt murine thymoma vial oncogene homolog 1 (AKT1), v-ras neuroblastoma viral oncogene homolog (NRAS), dual specificity mitogen-activated protein kinase kinase 1 (MEK1), and anaplastic lymphoma kinase (ALK) in patients with adenocarcinoma of the lung to identify driver mutations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The arrival of tyrosine kinase inhibitors (TKI) in first line of treatment for advanced non-small cell lung cancer with EGFR mutations has changed the strategy of treatment of theses patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[In this study, we evaluated the potential of a number of chemotherapeutics that demonstrate activity in HNSCC, including an inhibitor of epidermal growth factor receptor (EGFR) to potentiate the cytotoxic effects of lovastatin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Epidermal growth factor receptor R497K polymorphism is a favorable prognostic factor for patients with colorectal carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Panitumumab: in metastatic colorectal cancer with wild-type KRAS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Targeting the human EGFR family in esophagogastric cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Enhancement of lung carcinogenesis initiated with 4-(N-hydroxymethylnitrosamino)-1-(3-pyridyl)-1-butanone by Ogg1 gene deficiency in female, but not male, mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mammary adenocarcinomas induced by medroxyprogesterone acetate: hormone dependence and EGF receptors of BALB/c in vivo sublines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Analysis of EGFR, TGF-alpha, neu and c-myc in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced mammary tumors using RT-PCR.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The expression of epidermal growth factor receptor and Ki67 in primary and relapse nasopharyngeal cancer: a micro-evidence for anti-EGFR targeted maintenance therapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Targeted inhibition of transient activation of the EGFR-mediated cell survival pathway enhances paclitaxel-induced ovarian cancer cell death.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Hyperactive EGF receptor, Jaks and Stat3 signaling promote enhanced colony-forming ability, motility and migration of cisplatin-resistant ovarian cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A consistent phenotype observed in both human patients and several different mouse models of autosomal recessive polycystic kidney disease (ARPKD) is an increased activity of the epidermal growth factor receptor (EGFR) in the affected kidneys.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[We utilized two sublines of the DU145 human prostate carcinoma cell line that are genetically engineered to differentially activate the EGFR/PLCgamma cascade and are variously invasive in vitro and in vivo.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Antisense oligonucleotides (oligos) against transforming growth factor-alpha (TGF-alpha; MR(1)) and its binding site, the epidermal growth factor receptor (EGFR; MR(2)), have proven efficacious against PC-3 and LNCaP prostate tumors when evaluated in both in vitro and in vivo models.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Here, we present a case of an EGFR-mutant gefitinib-responsive non-small-cell lung cancer (NSCLC) of adenocarcinoma histology occurring in a never-smoker followed by subsequent diagnosis of metastatic SCLC carrying an EGFR mutation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Three-gene predictor of clinical outcome for gastric cancer patients treated with chemotherapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Impact of epidermal growth factor receptor expression on disease-free survival and rate of pelvic relapse in patients with advanced cancer of the cervix treated with chemoradiotherapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) activation suppresses ischemic induction of Egr-1 and its inflammatory gene targets.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Early growth response factor-1 limits biliary fibrosis in a model of xenobiotic-induced cholestasis in mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Disrupting reconsolidation of drug memories reduces cocaine-seeking behavior.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Cue-induced cocaine seeking and relapse are reduced by disruption of drug memory reconsolidation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Relapse to cocaine seeking increases activity-regulated gene expression differentially in the prefrontal cortex of abstinent rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Aldose reductase decreases endoplasmic reticulum stress in ischemic hearts.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Phosphorylation of the alpha subunit of translation initiation factor-2 by PKR mediates protein synthesis inhibition in the mouse brain during status epilepticus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Arginine deficiency causes runting in the suckling period by selectively activating the stress kinase GCN2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Association of hereditary prostate cancer gene polymorphic variants with sporadic aggressive prostate carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Double de novo mutations of ELA2 in cyclic and severe congenital neutropenia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[To identify genes involved in vascular disease, we investigated patients with supravalvular aortic stenosis (SVAS), an inherited vascular disorder that causes hemodynamically significant narrowing of large elastic arteries.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Homozygosity for a missense mutation in fibulin-5 (FBLN5) results in a severe form of cutis laxa.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Efforts to understand the pathogenesis of pulmonary fibrosis have focused primarily upon collagen turnover in the lung; few studies have focused on elastin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Adenocarcinoma of the lung with miliary brain and pulmonary metastases with echinoderm microtubule-associated protein like 4-anaplastic lymphoma kinase translocation treated with crizotinib: a case report.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Isolated central nervous system progression on Crizotinib: an Achilles heel of non-small cell lung cancer with EML4-ALK translocation?]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[While understanding molecular mechanisms of resistance is critical to overcome therapeutic resistance, understanding physiologic mechanisms of resistance through analyzing anatomic patterns of failure may be equally crucial to improve long-term survival for patients with EML4-ALK translocation positive NSCLC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Development of the mammalian female reproductive tract.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[EMX2 is epigenetically silenced and suppresses growth in human lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[The En2 gene, coding for the homeobox-containing transcription factor Engrailed-2 (EN2), has been associated to autism spectrum disorder (ASD).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[ENG and ACVRL1 genes code for proteins involved in the transforming growth factor beta pathway and it is widely accepted that haploinsufficiency is the origin for the pathogenicity of HHT.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Proteomic identification of HNE-bound proteins in early Alzheimer disease: Insights into the role of lipid peroxidation in the progression of AD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Increased expression of enolase alpha in human breast cancer confers tamoxifen resistance in human breast cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Increased neuron specific enolase expression by urothelial cells exposed to or malignantly transformed by exposure to Cd or As.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[We have found that plasma LPA level and serum autotaxin (ATX) activity were increased in patients with chronic hepatitis C. However, the clinical significance of LPA and its synthetic enzyme, autotaxin (ATX), is still unclear.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Establishment of clonal colony-forming assay for propagation of pancreatic cancer cells with stem cell properties.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[We identified recessive mutations in EPG5 (previously KIAA1632), indicating a causative role in Vici syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Role of microsomal epoxide hydrolase in methamphetamine-induced drug dependence in mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Mutant alleles of EPHX were significantly overrepresented in persons with HCC, also in a case-control study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[A comparison of transcriptomic and metabonomic technologies for identifying biomarkers predictive of two-year rodent cancer bioassays.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Application of genomic biomarkers to predict increased lung tumor incidence in 2-year rodent cancer bioassays.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[PCR-RFLP-based genotyping assays were used to determine the frequency of polymorphisms in CYP1A1 (3'-flanking region), CYP2E1 (5'-flanking region and intron 6), EPHX (exons 3 and 4), GSTM1 (deletion), GSTP1 (exon 5) and GSTT1 (deletion) in a case-control study comprised of 219 patients with morbus Hodgkin (MH) and non-Hodgkin's lymphomas (NHL) and 455 age- and sex-matched healthy individuals.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Two exonic single nucleotide polymorphisms in the microsomal epoxide hydrolase gene are jointly associated with preeclampsia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[We investigated whether polymorphisms in the gene for microsomal epoxide hydrolase (mEPHX), an enzyme involved in this protective process, had any bearing on individual susceptibility to the development of chronic obstructive pulmonary disease (COPD) and emphysema.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Erythropoietin gene-enhanced marrow mesenchymal stromal cells decrease cisplatin-induced kidney injury and improve survival of allogeneic mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Human recombinant erythropoietin (rHuEpo) that is used for the treatment of the chemotherapy-induced anaemia in cancer patients was shown to cause detrimental effects on the course of disease due to increased adverse events inflicting patient's survival, potentially related to rHuEpo-induced cancer progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Nifedipine and haemolytic anaemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Erythropoietin protects against doxorubicin-induced cardiomyopathy via a phosphatidylinositol 3-kinase-dependent pathway.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Synergistic benefits of erythropoietin and simvastatin after traumatic brain injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Erythropoietin is beneficial in mitomycin-induced hemolytic-uremic syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[We compared blood pressure after three different methods of partial correction of anemia in hemodialysis patients with similar baseline hematocrits (erythropoietin n = 12, intravenous iron alone n = 10, androgens n = 9).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Erythropoietin regulates apoptosis, inflammation and tissue remodelling via caspase-3 and IL-1 in isolated hemoperfused kidneys.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[To elucidate the role of Epo and erythropoietin receptor (EpoR) in melanoma, we examined the expression and function of these proteins in melanocytes and melanoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Long-term erythropoietin therapy improves response in myelodysplastic syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[We report the case of a 50-year-old body-builder Caucasian man with a long-standing abuse of nandrolone and erythropoietin that developed a ventricular septal defect following acute myocardial infarction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Erythropoietin (Epo) and the epo-receptor (EpoR) have been implicated in tumor growth, invasion and metastasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Therapeutic effects of rhEPO, rhG-CSF on sulfur mustard induced toxicity in dogs].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Protective effect of recombinant human erythropoietin against cisplatin-induced oxidative stress and nephrotoxicity in rat kidney.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Neuroprotective effects of erythropoietin in the rat hippocampus after pilocarpine-induced status epilepticus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Erythropoietin pretreatment protects against acute chemotherapy toxicity in isolated rat hearts.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[In contrast to the acquired MPDs, mutations of the erythropoietin receptor and thrombopoietin receptor have been identified in familial forms of nonclonal erythrocytosis and thrombocytosis, respectively.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Erythropoietin in thyroid cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[HER2 Testing in Gastric/Gastroesophageal Junction Adenocarcinomas: Unique Features of a Familiar Test.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Immunophenotypic predictive profiling of BRCA1-associated breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Mouse breast cancer model-dependent changes in metabolic syndrome-associated phenotypes caused by maternal dioxin exposure and dietary fat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Relevance of breast cancer antiestrogen resistance genes in human breast cancer progression and tamoxifen resistance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[HER-2/neu is expressed in human renal cell carcinoma at heterogeneous levels independently of tumor grading and staging and can be recognized by HLA-A2.1-restricted cytotoxic T lymphocytes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Increased ErbB-2 tyrosine kinase activity, MAPK phosphorylation, and cell proliferation in the prostate cancer cell line LNCaP following treatment by select pesticides.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Double high-dose chemotherapy followed by autologous peripheral blood stem cell transplantation for primary disseminated medulloblastoma: a report of 3 cases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Switching off HER-2/neu in a tetracycline-controlled mouse tumor model leads to apoptosis and tumor-size-dependent remission.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Polymorphism in the ERCC2 codon 751 is associated with arsenic-induced premalignant hyperkeratosis and significant chromosome aberrations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Association of XPD polymorphisms with prostate cancer in Taiwanese patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Polymorphisms in XPD (Asp312Asn and Lys751Gln) genes, sunburn and arsenic-related skin lesions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Xeroderma pigmentosum group D 751 polymorphism as a predictive factor in resected gastric cancer treated with chemo-radiotherapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Decreased DNA repair gene expression among individuals exposed to arsenic in United States drinking water.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Cerebro-oculo-facio-skeletal syndrome: three additional cases with CSB mutations, new diagnostic criteria and an approach to investigation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Manitoba aboriginal kindred with original cerebro-oculo- facio-skeletal syndrome has a mutation in the Cockayne syndrome group B (CSB) gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Moreover, the identification of a new ERG isoform (ERG3Deltaex12) suggests the association with different interaction partners and adds to the complexity of downstream pathways mediated by the expression of specific ERG transcripts in acute leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Patients with CN-AML harboring mutations in NPM1, FLT3, CEBPA, WT1 or expressing high levels of BAALC, ERG, or MN1 have distinctly different clinical outcomes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Exome sequencing supports a de novo mutational paradigm for schizophrenia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[ER-alpha activation was specifically associated with arsenic-induced lung adenocarcinoma and adenoma but not with nitrosamine-induced lung tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Herein, the expression of estrogen receptor alpha (ERalpha), estrogen receptor beta (ER beta) and progesterone receptor (PR) was examined in mammary gland carcinomas induced by PhIP in female Sprague-Dawley rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[The estrogen receptor 1 G594A polymorphism is associated with migraine susceptibility in two independent case/control groups.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Estrogen receptor variation also has potential to explain recent conflicting data regarding the effects of hormone therapy on CVD susceptibility in women.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Quantitative profiles of the mRNAs of ER-alpha and its novel variant ER-alpha36 in breast cancers and matched normal tissues.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Regulation and expression of human CYP7B1 in prostate: overexpression of CYP7B1 during progression of prostatic adenocarcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[c-erbB-2 and the `triple-state` in early breast carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[ERbeta isoform expression in colorectal carcinoma: an in vivo and in vitro study of clinicopathological and molecular correlates.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Acute dilatation to phytoestrogens and estrogen receptor subtypes expression in small arteries from women with coronary heart disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Taken together, methylation of a CpG island at the ESR2 promoter region is a primary mechanism responsible for differential expression of ESR2 in endometriosis and endometrium.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Apigenin suppresses cancer cell growth through ERbeta.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Estrogen-related receptors as emerging targets in cancer and metabolic disorders.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Complex contributions of Ets2 to craniofacial and thymus phenotypes of trisomic `Down syndrome` mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Integrative molecular concept modeling of prostate cancer progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Ewing sarcoma (ES), a highly malignant pediatric tumor, is consistently associated with translocations that fuse the EWS gene with a member of the ETS family gene, most commonly FLI-1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Mutations in the EXT1 and EXT2 genes in Spanish patients with multiple osteochondromas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[We present a female with Cayler's cardiofacial syndrome phenotype who had a frameshift mutation of the EYA1 gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Screening of a total of 614 individuals with myeloid disorders revealed 49 monoallelic or biallelic EZH2 mutations in 42 individuals; the mutations were found most commonly in those with myelodysplastic/myeloproliferative neoplasms (27 out of 219 individuals, or 12%) and in those with myelofibrosis (4 out of 30 individuals, or 13%).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Microarray analyses in dendritic cells reveal potential biomarkers for chemical-induced skin sensitization.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Factor XIII Val34Leu is a genetic factor involved in the etiology of venous thrombosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[A familial factor XIII subunit B deficiency.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Tissue factor-deficiency and protease activated receptor-1-deficiency reduce inflammation elicited by diet-induced steatohepatitis in mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Vitamin E reduces monocyte tissue factor expression in cirrhotic patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Six proteins were identified as being up-regulated at least 2-fold in MAP+ cows including: transferrin, gelsolin isoforms & (actin binding protein - ABP), complement subcomponent C1r, complement component C3, amine oxidase - copper containing 3 (AOC3), and coagulation factor II (thrombin) (p<0.05).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Pharmacological effects of a novel recombinant hirudin, CX-397, in vivo and in vitro: comparison with recombinant hirudin variant-1, heparin, and argatroban.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Detection of factor V leiden and prothrombin gene mutations in patients who died with thrombotic events.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Using an established mouse model of Western diet-induced NAFLD, we tested whether the thrombin receptor protease-activated receptor 1 (PAR-1) and hematopoietic cell-derived tissue factor (TF) contribute to hepatic steatosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Protease-activated receptor-1 (hPar1), a survival factor eliciting tumor progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Role of fibrinogen and protease-activated receptors in acute xenobiotic-induced cholestatic liver injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Recipient tissue factor expression is associated with consumptive coagulopathy in pig-to-primate kidney xenotransplantation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[One month after treatment, TTP patients showed a significant decrease in plasma TM levels, and a significant increase in plasma TFPI levels, but plasma levels of TF antigen were not significantly increased.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.